摘要
基于自主研发的新型在线固相萃取系统和液相色谱串联质谱法建立了一种精密度高、准确性高且能快速检测分析水中痕量全氟化合物(PFCs)的方法。以乙酸水溶液及乙腈为流动相,利用电喷雾离子源(ESI)、负离子采集模式和质谱多反应监测模式(MRM)进行分析,实现了水中17种PFCs的高效准确分析,其检出限(S/N=3)范围为0.05~0.1 ng/L,相关系数(R^(2))均大于0.99,加标回收率在79%~93%之间。该方法应用于实际水样检测时,可检出多种短、长链PFCs。方法简化了在线固相萃取系统的样品前处理流程,优化测试条件,有望为水中痕量PFCs提供一种便捷、快速且准确的分析方法参考。
A novel methodology with high precision,accuracy,and rapid detection capability for trace perfluorinated compounds(PFCs)in aqueous matrices was established through the integration of a self-developed online solid-phase extraction(SPE)system with liquid chromatography-tandem mass spectrometry(LC-MS/MS).The sample pretreatment process was simplified using the online SPE system,while optimized chromatographic conditions were achieved through mobile phase selection(aqueous acetic acid and acetonitrile).Analytical detection was performed using electrospray ionization(ESI)in negative ion mode coupled with multiple reaction monitoring(MRM),enabling simultaneous quantification of 17 PFCs.The method exhibited exceptional sensitivity with detection limits(S/N=3)ranging from 0.05 to 0.1 ng/L,demonstrated excellent linearity(correlation coefficients R^(2)>0.99),and achieved satisfactory spike recoveries(79%~93%).Practical application to actual water samples revealed detectable levels of various short-and long-chain PFCs.The method simplifies the sample pretreatment process of the online SPE system and optimizes testing conditions,offering a promising reference for a convenient,rapid,and accurate analytical approach to detect trace levels of PFCs in water.
作者
王博
王声宇
陈妍妍
张亦弛
陈邵
WANG Bo;WANG Sheng-yu;CHEN Yan-yan;ZHANG Yi-chi;CHEN Shao(Nanjing Ecological Environment Monitoring and Control Center,Nanjing 210041,China)
出处
《环境科技》
2025年第3期69-73,共5页
Environmental Science and Technology
基金
南京市环保科研课题:有机氟化物富集降解集成技术研究(202305).
关键词
在线固相萃取
液相色谱-串联质谱
全氟化合物
地表水
地下水
On-line solid phase extraction
Liquid chromatography-tandem mass spectrometry
Perfluorinated compounds
Surface water
Underground water
