摘要
海洋是各种具有不同化学结构和生物活性的天然聚合物的宝库,多糖是海洋中最丰富的资源之一。褐藻来源的多糖,如岩藻多糖,不仅原料充足,而且具有多种重要的生理活性,例如抗氧化、抗肿瘤、提高免疫力、提高肝肾功能、降低血糖等。这些特性使其成为了极具药用价值的活性物质,在食品和生物医药等多个领域,岩藻多糖都展现出了巨大的应用潜力。与天然岩藻多糖相比,低分子量的岩藻多糖具有更高的水溶性、生物利用度及更强的益生元活性,因而备受学界关注。本文综述了岩藻多糖结构、提取、纯化和降解方法,对低分子量岩藻多糖生物活性的研究进行了总结和展望,旨在为进一步研究提供理论基础,并为海洋藻类资源的高值化开发利用提供参考。
The ocean is a treasure trove of natural polymers with diverse chemical structures and biological activities,among which polysaccharides represent one of the most abundant marine resources.Fucoidan,derived from brown algae,possesses significant biological activities,including antioxidant,anti-tumor,immune-boosting,liver and kidney functionimproving,and blood sugar-regulating effects.It has unique application values in food,medicine,and materials.Compared with natural fucoidan,low molecular weight fucoidan has higher water solubility and bioavailability,and stronger prebiotic activity,which has attracted much attention.This paper reviews the structure,extraction,purification,and degradation methods for the preparation of low molecular weight fucoidan,and summarizes and prospects the biological activity of low molecular weight fucoidan,which provides a theoretical basis for further study and a reference for the high-value development and utilization of marine algae resources.
作者
李燕妮
蔡怡瑾
王梓腾
胡亚东
潘明轩
杨文革
周兴虎
胡永红
LI Yanni;CAI Yijin;WANG Ziteng;HU Yadong;PAN Mingxuan;YANG Wenge;ZHOU Xinghu;HU Yonghong(College of Biotechnology and Pharmaceutical Engineering,Nanjing Tech University,Nanjing 211816,China;Jiangsu Coast Development Investment Co.,Ltd.,Nanjing 210019,China;School of Pharmaceutical Sciences,Nanjing Tech University,Nanjing 211816,China;College of Food Science and Light Industry,Nanjing Tech University,Nanjing 211816,China)
出处
《食品工业科技》
北大核心
2025年第13期383-394,共12页
Science and Technology of Food Industry
基金
江苏沿海开发投资有限公司海洋生物高值化开发利用项目(2023YHTZZZ02)
江苏省自然资源厅海洋科技创新项目(JSZRHYKJ202309)。
