摘要
目的:通过与常规针刺疗法对比,验证基于“辨经论治”理论针刺治疗中风后吞咽障碍肾经症状的临床疗效及对单胺类神经递质水平的影响,旨在为治疗中风后吞咽障碍提供新的思路和更加有效的治疗方案。方法:选取2022年5月—2023年5月就诊于安徽省针灸医院的中风后吞咽障碍患者64例,通过随机数字法分为治疗组和对照组,各32例,对照组采用常规局部取穴,治疗组采用“辨经”取穴+项部取穴+舌咽部取穴,每周治疗6 d,比较治疗4周后的疗效及血清单胺类神经递质含量的变化。结果:对照组脱落2例,治疗组脱落1例。治疗组的综合有效率为96.77%(30/31),对照组为80.00%(24/30),差异具有统计学意义(P<0.01);治疗组洼田饮水试验(WST)、标准吞咽功能评价量表(SSA)均显著改善(P<0.01),且改善幅度明显优于对照组(P<0.01);两组患者治疗前后血清单胺类神经递质差异具有统计学意义(P<0.01)。结论:“辨经论治”理论指导下的针刺法在治疗中风后吞咽障碍时优于常规取穴针刺法,且患者血清单胺类神经递质水平含量明显优于常规取穴针刺法。
Objective:To verify the clinical efficacy of acupuncture based on the theory of“Meridian Differentiation and Treatment”for treating kidney meridian symptoms of post-stroke swallowing disorders,and its effect on monoamine neurotransmitter levels,compared to conventional acupuncture methods.This study aims to provide new insights and more effective treatment options for post-stroke swallowing disorders.Methods:Sixty-four patients with post-stroke swallowing disorders who visited Anhui Provincial Acupuncture Hospital from May 2022 to May 2023 were selected.They were randomly divided into a treatment group and a control group,with 32 patients in each group.The control group received conventional local acupuncture,while the treatment group received acupuncture according to meridian differentiation combined with acupuncture at the cervical and Glossopharyngeal regions.Treatments were administered once a day and 6 days a week for 4 weeks.The efficacy and changes in serum monoamine neurotransmitter levels were compared after 4 weeks of treatment.Results:Two patients dropped out from the control group,and one from the treatment group.The comprehensive efficacy rate in the treatment group was 96.77%(30/31),compared to 80.00%(24/30)in the control group,with a statistically significant difference(P<0.01).The treatment group showed significant improvements in the WST,SSA,MMASA,and TCM symptom scoring scales(P<0.01),with improvements significantly exceeding those in the control group(P<0.01).The differences in serum monoamine neurotransmitter levels before and after treatment were statistically significant in both groups(P<0.01).Conclusion:Acupuncture guided by the meridian differentiation and treatment theory is superior to conventional acupuncture methods in treating post-stroke swallowing disorders,and it also significantly improves serum monoamine neurotransmitter levels compared to conventional acupuncture.
作者
张世林
程红亮
顾伟
徐渊
王强
汪庆庆
ZHANG Shilin;CHENG Hongliang;GU Wei;XU Yuan;WANG Qiang;WANG Qingqing(Fuyang Sixth People's Hospital,Fuyang 236000,China;Anhui Provincial Acupuncture Hospital,Hefei 230001,China)
出处
《中医药学报》
2025年第5期47-51,共5页
Acta Chinese Medicine and Pharmacology
基金
安徽省卫生健康委重点项目(AHWJ2021A020)。
关键词
辨经论治
中风后吞咽障碍
单胺类神经递质
针刺
Meridian differentiation and treatment
Post-stroke swallowing disorders
Monoamine neurotransmitters
Acupuncture
