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制药综合实验课程的探索和实践——以对乙酰氨基酚为例

Exploration and Practice of Pharmaceutical Comprehensive Experimental Course:Acetaminophen as An Example
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摘要 制药综合实验是制药工程本科专业的核心课程。本文更新实验教学内容,优化了关于对乙酰氨基酚的制药综合性实验。实验内容包括对乙酰氨基酚的合成与精制,鉴别检查,片剂制备、溶出度测定和镇痛作用评价。该实验可以使学生掌握或熟悉一般化药的有机合成、精制、鉴定分析、制剂制备、药效评价、数据统计分析等重要技能,并熟悉药物研发流程。设计学科交叉的综合性实验,提高了学生综合实验技能和专业素养,并激发了学生的学习兴趣,对提高实验教学质量具有重要作用。 Pharmaceutical comprehensive experiment is a core course in the undergraduate program of pharmaceutical engineering.This article updates the experimental contents of course,which optimizes the pharmaceutical comprehensive experiment on acetaminophen.The experimental content includes the synthesis and purification of acetaminophen,identification and inspection,tablet preparation,dissolution determination,as well as analgesic effect evaluation.This experiment can enable students to master or become familiar with important skills such as organic synthesis,refining,identification and analysis,tablet preparation,efficacy evaluation,and data statistical analysis,as well as familiarize themselves with the general process of drug development.Designing interdisciplinary comprehensive experiments has improved students'comprehensive experimental skills and professional literacy,and stimulated their interest in learning,which is of great importance for improving experimental teaching.
作者 马猛华 臧永军 鲍玲玲 陈艳君 朱富成 Ma Menghua;Zang Yongjun;Bao Lingling;Chen Yanjun;Zhu Fucheng(Wanxi University,Luan 237012,China)
机构地区 皖西学院
出处 《广东化工》 2025年第10期178-180,共3页 Guangdong Chemical Industry
基金 皖西学院教育教学研究项目:工程认证背景下以提升学生就业能力为导向的《药品生产质量管理工程》课程改革研究(wxxy2023074) 皖西学院下线课程:制药设备与工程设计(wxxy2023034) 安徽省新时代高校党建示范创建和质量创优项目(2023ybzb163)。
关键词 制药综合实验 对乙酰氨基酚 有机合成 鉴别分析 pharmaceutical comprehensive experiment acetaminophen organic synthesis identification and analysis
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