摘要
介绍了一种合成1-(4′-磺酸基苯基)-3-羧酸甲酯-5-吡唑啉酮单钾盐的方法,以对氨基苯磺酸和DMAS为原料,经重氮、缩合闭环及钾盐取代等步骤制得。高效液相色谱检测纯度>92%,可作为标准样品应用于食品添加剂柠檬黄的检测,对其进行定性与定量分析,具有重要的实际意义和研究价值。
A synthetic method for 1H-Pyrazole-3-carboxylic acid,4,5-dihydro-5-oxo-1-(4-sulfophenyl)-,3-methyl ester,potassium salt was introduced with 4-Amino-benzenesulfonic acid monosodium salt and DMAS as raw materials.The synthesis involved diazotization,cyclization,and potassium salt substitution.Determined by high-performance liquid chromatography(HPLC),the purity exceeded 92%.This compound can serve as a reference material for the detection of the food additive tartrazine,offering significant practical and research value in the qualitative and quantitative analysis.
作者
柴钧彦
CHAI Junyan(Shanghai Dyestuffs Research Institute Co.,Ltd.,Shanhai 200065,China)
出处
《上海染料》
2025年第2期36-38,共3页
Shanghai Dyestuffs
