摘要
近年来,维生素K除了凝血功能之外,还表现出防治骨质疏松、改善心血管疾病、预防糖尿病及特定癌症等多方面的潜在健康效应。本文从生理功能以及转运转化、吸收利用、储存排泄等方面入手,阐述了维生素K_(1)和维生素K_(2)的异同,并综述了维生素K的形式、膳食组成及基因多态性(APOE,VKOR,CYP4F2等)对维生素K代谢的影响,为后续维生素K与相关疾病的研究及膳食参考摄入量的制订提供参考。
In recent years,the different types of vitamin K have shown potential health effects on prevention and treatment of osteoporosis,improvement of cardiovascular disease,prevention of diabetes and some types of cancer,in addition to coagulation function.In this review,the physiological function of vitamin K,and the similarities and differences between vitamin K_(1) and vitamin K_(2) in terms of their absorption,transport,storage and excretion in the human body are discussed.The effects of different types of vitamin K,dietary composition and gene polymorphism(APOE,VKOR,CYP4F2,etc.)on vitamin K metabolism were also outlined to provide a reference for future study and the development of dietary reference intakes.
作者
王海燕
聂淑慧
胡贻椿
杨晓光
WANG Hai-yan;NIE Shu-hui;HU Yi-chun;YANG Xiao-guang(Nutritional Institute for Nutrition and Health,Chinese Center for Disease Control and Prevention,Key Laboratory of Trace Element andNutritionof theHealthCommission,Beijing100050,China)
出处
《营养学报》
北大核心
2025年第1期92-98,共7页
Acta Nutrimenta Sinica
基金
中国健康促进基金会营养促进专项基金(No.Z093001)。
关键词
维生素K
生理功能
吸收
代谢
vitamin K
physiological function
adsorption
metabolism
