摘要
目的分析某三甲医院大肠癌伺机性筛查结果及大肠癌发生的危险因素。方法选择2022年1月至2023年2月空军军医大学西京医院接收的950例健康体检和普通就诊人群作为调查对象,通过问卷调查和粪便隐血试验进行初步筛查,对初步筛查后高危人群行肠镜检查。并根据检查结果将240例大肠癌及大肠息肉患者分为大肠癌组34例和非大肠癌组206例,分析大肠癌发生的影响因素。结果240例患者中,初步筛查高危人群159例,所占比例为66.25%(159/240);男性检出率为70.73%(116/164)明显高于女性的56.58%(43/76)(P<0.05);年龄70~89岁检出率为81.13%(43/53),明显高于年龄29~49岁的47.83%(11/23)及年龄50~69岁的64.02%(105/164)(P<0.05)。在不同年龄阶段分布中,进展期腺瘤、大肠癌检出率相比差异均有统计学意义(P<0.05)。大肠癌组年龄70~89岁、黏液血便史、一级亲属肠癌史、大肠息肉史及个人非大肠癌肿瘤史比例均明显高于非大肠癌组(P<0.05)。黏液血便史、一级亲属肠癌史、个人非大肠癌肿瘤史是影响居民患大肠癌的独立危险因素(P<0.05)。结论大肠癌伺机性筛查能有效筛出高危人群,有利于大肠癌的早期确诊。
Objective To analyze the results of opportunistic screening of colorectal cancer and the risk factors of colorectal cancer in a top three hospital.Methods From January 2022 to February 2023,950 patients received by Xijing Hospital of Air Force Military Medical University for physical examination and general treatment were selected as the investigation objects.Preliminary screening was conducted through questionnaire survey and fecal occult blood test,colonoscopy was performed on high-risk groups after preliminary screening.According to the examination results,240 patients with colorectal cancer and polyps were divided into colorectal cancer group(34 cases)and non-colorectal cancer group(206 cases),analyze the influencing factors of colorectal cancer.Results Among the 240 patients,159 cases of high-risk group were preliminatively screened,accounting for 66.25%(159/240);the detection rate of 70.73%(116/164)in males was significantly higher than that of 56.58%(43/76)in females(P<0.05);the detection rate was 81.13%(43/53)at the age of 70-89,significantly higher than 47.83%(11/23)at the age of 29-49 and 64.02%(105/164)at the age of 50-69(P<0.05).In the distribution of different age stages,the detection rate of advanced adenoma and colorectal cancer had statistical significance(P<0.05).The percentages of age 70-89 years old,history of mucous blood stool,first degree relatives′history of colorectal cancer,colorectal polyp history and personal history of non-colorectal cancer in colorectal cancer group were significantly higher than those in non-colorectal cancer group(P<0.05).The history of mucous blood stool,first degree relatives′history of colorectal cancer and personal history of non-colorectal cancer were the independent risk factors for colorectal cancer(P<0.05).Conclusion Opportunistic screening of colorectal cancer can effectively screen out high-risk groups,which is conducive to early diagnosis of colorectal cancer.
作者
杨志娟
潘妍
杜方伶
张雪娟
王菲
YANG Zhijuan;PAN Yan;DU Fangling;ZHANG Xuejuan;WANG Fei(Department of Gastroenterology,Xijing Hospital of Air Force Military Medical University,Xi′an 710032,China;Digestive Endoscopy Center,Honghui Hospital Affiliated to Xi′an Jiaotong University School of Medicine,Xi′an 710061,China;Department of Orthopedics,Xijing Hospital of Air Force Military Medical University,Xi′an 710032,China)
出处
《现代消化及介入诊疗》
2025年第2期142-145,共4页
Modern Interventional Diagnosis and Treatment in Gastroenterology
基金
国家自然科学基金项目(82373117)。
关键词
大肠癌
伺机性筛查
高危人群
检出率
影响因素
colorectal cancer
opportunistic screening
high-risk population
detection rate
influence factor
