摘要
病毒性肝炎及相关肝病是全球最重要的医疗保健问题之一。病毒性肝炎不仅直接影响肝脏功能,还通过肠肝轴与肠道菌群产生相互作用。肠道菌群失衡可能与病毒性肝炎及相关肝病的发生、发展和预后有关。对肠道菌群的检测和分析有助于更全面地了解病毒性肝炎及相关肝病患者的健康状况,为疾病的早期诊断提供依据。肠道菌群紊乱的恢复可能有助于减轻肝脏炎症、改善肝功能,通过粪便微生物群移植、益生菌及益生元等手段调节肠道菌群可能是治疗病毒性肝炎及相关肝病的新策略。本文通过分析肠道菌群在病毒性肝炎及相关肝病中的最新研究进展,为病毒性肝炎及相关肝病的诊断和治疗提供新手段。
Viral hepatitis and related liver diseases are among the most significant global healthcare issues.Viral hepatitis not only directly affects liver function but also interacts with the gut microbiota through the gut-liver axis.Imbalance in the gut microbiota may be associated with the occurrence,development and prognosis of viral hepatitis and related liver diseases.Detection and analysis of the gut microbiota can help to comprehensively understand the health status of patients with viral hepatitis and related liver diseases,providing a basis for early diagnosis.Recovery of gut microbiota dysbiosis may help to alleviate liver inflammation and to improve liver function.Regulating the gut microbiota through gut microbiota transplantation,probiotics and prebiotics may be new strategies for treating viral hepatitis and related liver diseases.By analyzing the latest research progress of gut microbiota in viral hepatitis and related liver diseases,this article provides new methods for the diagnosis and treatment of viral hepatitis and related liver diseases.
作者
于建秀
宣世海
吴李培
李红红
吴健
Yu Jianxiu;Xuan Shihai;Wu Lipei;Li Honghong;Wu Jian(Department of Laboratory Medicine,Affiliated Dongtai Hospital of Nantong University,Dongtai 224200,China;Department of Laboratory Medicine,Afiliated Suzhou Hospital of Nanjing Medical University,Suzhou215008,China)
出处
《中华检验医学杂志》
北大核心
2025年第4期532-537,共6页
Chinese Journal of Laboratory Medicine
关键词
病毒性肝炎
肝硬化
肝细胞癌
肝衰竭
肠道菌群
Viral hepatitis
Liver cirrhosis
Hepatocellular carcinoma
Liver failure
Gutmicrobiota
