摘要
行为学研究表明中枢八肽胆囊收缩素(CCK-8)在电针耐受和吗啡耐受中发挥重要作用。本文研究表明,电针耐受时大鼠脑脊液中CCK-8样免疫活性物质(CCK-8-ir)的浓度增高,中脑导水管周围灰质内的CCK-8-ir的含量也明显增加,并观察到在急性吗啡耐受时大鼠脑脊液中CCK-8-ir的浓度增高。
Behavioural studies suggest that cholecystokinin octapeptide(CCK-8)plays an important role in the development of tolerance lo electroacupuncturc(EA)analgesia and morphine analgesia.Observations made in this study revealed an increase of CCK-8 inmunoreactivity(CCK-8-ir)in bothCSFand PAG in EA tolerant rats as well as an increaseofCCK-8-irin CSFin rats rendered tolerant to morphine.
作者
周岩
孙宇华
朴素芬
韩济生
Zhou Yan;Sun Yuhua;Pu Sufen;Han Jisheng(Beijing Medical University,Neuroscience Research Center,Beijing 100083)
出处
《针刺研究》
CSCD
1991年第3期227-228,共2页
Acupuncture Research
