摘要
Alzheimer’s disease(AD)remains clinically incurable,raising a significant public health issue,particularly with its continuously increased incidence.1 Inflammatory bowel disease,including ulcerative colitis and Crohn’s disease(CD),is characterized by long-standing inflammation and immunological imbalance of the gastrointestinal system.2 Recent epidemiological studies suggest a link between increased AD risk and inflammatory bowel disease.
基金
supported by the Key R&D Program of the Science and Technology Ministry of China(No.2021YFC2701100)
the National Natural Science Foundation of China(No.82150008,81930036)。