摘要
目的分析神经内镜下经鼻蝶入路垂体瘤切除手术对脑垂体瘤患者的疗效。方法将86例脑垂体瘤患者随机分为两组,均43例。对照组行显微镜下经鼻蝶入路垂体瘤切除术,观察组行神经内镜下经鼻蝶入路垂体瘤切除术。对比两组手术效果。结果观察组术中出血量为(75.42±4.29)ml,少于对照组的(80.78±5.32)ml;观察组手术时间为(86.21±3.48)min、住院时间为(8.23±1.35)d,短于对照组的(90.34±4.35)min、(10.16±1.97)d。观察组并发症发生率为4.65%(2/43),低于对照组[18.60%(8/43)]。观察组术后的皮质醇(Cor)为(310.54±22.58)nmol/L、促肾上腺皮质激素(ACTH)为(17.23±3.02)pmol/L、视野模式标准差(PSD)为(3.05±0.59)dB,均低于对照组[(324.98±26.72)nmol/L、(19.95±3.57)pmol/L、(3.88±0.71)dB]。观察组视野平均缺损值(MD)为(-3.69±0.31)dB、视野指数(VFI)为(90.42±9.36)%,均高于对照组[(-5.41±0.58)dB、(83.95±7.25)%](P<0.05)。结论神经内镜下经鼻蝶入路垂体瘤切除手术创伤小、恢复快,引起的应激反应较轻,可有效改善患者视觉功能,且并发症少。
Objective To analyze the efficacy of endoscopic transnasal transsphenoidal pituitary tumor resection surgery for patients with pituitary tumors.Methods 86 patients with pituitary tumors were randomly divided into 2 groups,with 43 cases in each group.The control group underwent endoscopic transnasal transsphenoidal pituitary tumor resection,while the observation group underwent endoscopic transnasal transsphenoidal pituitary tumor resection.Compared the surgical outcomes of the 2 groups.Results The intraoperative blood loss in the observation group was(75.42±4.29)ml,which was less than the control group's(80.78±5.32)ml.The operation time was(86.21±3.48)minutes,and the hospitalization time was(8.23±1.35)days,which was shorter than the control group's(90.34±4.35)minutes and(10.16±1.97)days.The incidence of complications was 4.65%(2/43),which was lower than the control group's[18.60%(8/43)];And the postoperative cortisol(Cor)was(310.54±22.58)nmol/L,adrenocorticotropic hormone(ACTH)was(17.23±3.02)pmol/L,and visual field pattern standard deviation(PSD)was(3.05±0.59)dB,all lower than the control group[(324.98±26.72)nmol/L,(19.95±3.57)pmol/L,(3.88±0.71)dB].The average visual field defect value(MD)of the observation group was(-3.69±0.31)dB,and the visual field index(VFI)was(90.42±9.36)%,all higher than the control group[(-5.41±0.58)dB,(83.95±7.25)%](P<0.05).Conclusion Transnasal transsphenoidal pituitary tumor resection surgery under neuroendoscopy has advantages such as minimal trauma,fast recovery,mild stress response,effective improvement of visual function in patients with pituitary tumors,and fewer complications.
作者
王贵聪
雷彤彤
刘雷震
张圣旭
WANG Guicong;LEI Tongtong;LIU Leizhen(Kaifeng Central Hospital,Kaifeng,475000)
出处
《实用癌症杂志》
2025年第4期676-678,共3页
The Practical Journal of Cancer
关键词
脑垂体瘤
应激反应
并发症
Pituitary tumor
Stress response
Complications
