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Glycoalkaloids:Structural diversity and pharmacological activities

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摘要 Glycoalkaloids(GAs)are a class of special secondary metabolites found in plants.Studies have found that they have a wide range of pharmacological activities,such as antiviral,antifungal,and anticancer properties,with significant potential for development and utilization value.At present,alkaloid glucosides mainly fall into 2 categories:indole alkaloid glucosides and steroid alkaloid glucosides.In addition,there are small amounts of quinolines,isoquinolines,isoguanines,and other alkaloids.At present,only a few of the GAs have been found,which is inconsistent with the diversity of alkaloids.In addition,only a few GAs have been isolated and identified.This paper reviews the natural alkaloid glycosides from the perspectives of structural classification and pharmacological activity.It analyzes the reasons for the limited number of isolated components and proposes a rational separation method based on the literature.To provide references for the separation,identification,and bioactivity of glycoalkaloids.
出处 《Guideline and Standard in Chinese Medicine》 2024年第2期44-61,共18页 中医规范与标准(英文)
基金 supported by the National Natural Science Foundation of China(No.82073978) the Fundamental Research Funds for the Central Universities(No.2023-JYBJBZD-048 and 2022-JYB-JBZR-015).
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