摘要
多学科交叉融合的诊疗方式极大推动了医学诊断和治疗模式。近年来,CRISPR-Cas9基因编辑、多模态人工智能诊断模型、达芬奇手术机器人以及基因检测技术在医疗领域广泛应用,这些学科优势的融合交叉逐步形成了肿瘤诊疗的新范式。本综述将从基因诊断、基因编辑和肿瘤精准治疗、虚拟现实、人工智能与大数据、机器人外科手术、肠道微生物与肿瘤微环境等方面阐述肿瘤诊疗的变革过程。依托学科优势并结合新兴技术是响应学科交叉国家战略的重要举措,对推动学科交叉肿瘤诊疗新范式的建设具有重要意义。
The interdisciplinary integration of diagnosis and treatment methods has greatly promoted the medical diagnosis and treatment models.In recent years,CRISPR-Cas9 gene editing,multimodal artificial intelligence diagnostic models,Da Vinci surgical robots,and gene detection technologies have been widely applied in the medical field.The integration and intersection of these disciplinary advantages have gradually formed a new paradigm for tumor diagnosis and treatment.This review will elaborate on the transformation process of tumor diagnosis and treatment from aspects such as gene diagnosis,gene editing and precise tumor treatment,virtual reality,artificial intelligence and big data,robotic surgery,and the intestinal microbiota and tumor microenvironment.Leveraging disciplinary expertise and integrating emerging technologies are critical strategies in response to national policies,and it holds substantial significance for advancing the construction of an innovative paradigm in interdisciplinary oncology diagnosis and treatment.
作者
张万广
陈孝平
Wanguang Zhang;Xiaoping Chen(Tongji Hospital,Tongji Medical College,Huazhong University of Science and Technology,Wuhan 430030,China)
出处
《中国科学基金》
北大核心
2025年第1期132-143,共12页
Bulletin of National Natural Science Foundation of China
基金
国家自然科学基金项目(82173319,U23A20483)
华中科技大学同济医学院附属同济医院高质量临床研究基金项目(2024TJCR004)的资助。
关键词
学科交叉
肿瘤基因诊疗
虚拟现实
大数据
肠道菌群
interdisciplinary
tumor gene diagnosis and treatment
virtual reality
big data
gut microbes
