摘要
目的 探讨七味白术散加减在小儿肺脾气虚型腺样体肥大患儿治疗中的效果。方法 选择2022年5月—2024年4月东莞市清溪医院耳鼻喉门诊就诊的小儿肺脾气虚型腺样体肥大患儿80例,采用随机数字表法,按1∶1的比例分为对照组(40例,常规西药治疗)与治疗组(40例,七味白术散加减联合常规西药治疗)。比较2组患儿治疗后的中医证候积分、生活质量状况量表(disease specific quality of for children with obstructive sleep apnea 18 items survey,OSA-18)、再次复发时间和治疗效果。结果 治疗后,治疗组中医证候积分中主证积分、次症积分、腺样本体积积分分别为(14.21±3.59)分、(2.64±0.55)分、(3.24±0.94)分,低于对照组的(16.87±4.01)分、(3.12±1.01)分、(4.29±0.78)分,差异均有统计学意义(P <0.05);治疗15、30 d后,治疗组OSA-18总分值分别为(84.14±8.22)分、(74.63±7.38)分,低于对照组(90.58±10.47)分、(79.36±8.94)分,差异均有统计学意义(P <0.05)。治疗组的治疗总有效率为92.50%,高于对照组的75.00%,差异有统计学意义(P <0.05);治疗组治疗后腺样体相关症状再次复发时间为(30.36±4.78)d,长于对照组的(17.58±2.24)d,差异有统计学意义(P <0.001)。结论 小儿肺脾气虚型腺样体肥大患儿采用七味白术散加减并结合孟鲁司特钠与糠酸莫米松鼻喷剂治疗,能够改善患儿的临床症状,延长复发时间,提高治疗效果,使患儿生活质量得到提升。
Objective To explore the effect of Qiwei Baizhu powder in the treatment of adenoid hypertrophy with lung and spleen qi deficiency in children.Methods Eighty children with adenoid hypertrophy of lung and spleen qi deficiency who visited the ENT outpatient department of Dongguan Qingxi Hospital from May 2022 to April 2024 were selected as the survey objects.They were divided into a control group(40 cases,treated with conventional western medicine)and a control group(40 cases,treated with modified Qiwei Baizhu Powder combined with conventional western medicine)at a ratio of 1:1 using the random number table method.The TCM syndrome scores,quality of life status scale(disease specific quality of for children with obstructive sleep apnea 18 items survey,OSA-18),recurrence time and treatment effect of the two groups of children after treatment were compared.Results After treatment,the scores of main symptoms,secondary symptoms and adenoid sample volume in the TCM syndrome score of the treatment group were(14.21±3.59)points,(2.64±0.55)points and(3.24±0.94)points respectively,which were all lower than[(16.87±4.01)points,(3.12±1.01)points and(4.29±0.78)points]of the control group,the differences were statistically significant(P<0.05).15 days and 30 days after treatment,the total OSA-18 scores of the treatment group were(84.14±8.22)points and(74.63±7.38)points respectively,which were lower than(90.58±10.47)points and(79.36±8.94)points of the control group,and the differences were statistically significant(P<0.05).The total effective rate of the treatment group was 92.50%,which was higher than 75.00%of the control group,the difference was statistically significant(P<0.05).The recurrence time of adenoid-related symptoms after treatment in the treatment group was(30.36±4.78)days,which was longer than that of the control group[(17.58±2.24)days],the difference was statistically significant(P<0.001).Conclusion For children with adenoid hypertrophy of lung and spleen qi deficiency,modified Qiwei Baizhu Powder combined with montelukast sodium and mometasone furoate nasal spray for treatment can improve the clinical symptoms of children,prolong the recurrence time,enhance the treatment effect,and improve the quality of life of children.
作者
叶永青
杨文权
刘丽婷
陈小玲
YE Yongqing;YANG Wenquan;LIU Liting;CHEN Xiaoling(Department of Pediatrics,Dongguan Qingxi Hospital,Dongguan Guangdong 523660,China;Department of Otolaryngology,Dongguan Qingxi Hospital,Dongguan Guangdong 523660,China;Hemodialysis Room,Dongguan Qingxi Hospital,Dongguan Guangdong 523660,China)
出处
《中国卫生标准管理》
2025年第2期151-154,共4页
China Health Standard Management
基金
2022年东莞市社会发展科技项目面上项目(20221800900852)。
关键词
七味白术散
孟鲁司特钠
糠酸莫米松鼻喷剂
肺脾气虚型
腺样体肥大
生活质量
中医证候积分
Qiwei Baizhu powder
montelukast sodium
mometasone furoate nasal spray
lung and spleen qi deficiency
adenoid hypertrophy
quality of life
TCM syndrome score
