摘要
目的评价疾病负担系统评价/Meta分析的方法学质量,并剖析其影响因素,为提高相关研究的方法学质量提供参考依据。方法计算机检索PubMed数据库,检索时限为建库至2024年10月12日;纳入疾病负担系统评价/Meta分析,使用AMSTAR-2条目评价纳入文献的方法学质量,并使用Excel 2021提取数据。结果共纳入308篇疾病负担系统评价/Meta分析,2006年至2024年发表文献数量呈波动上升趋势;其中,共有12篇文献被评为低质量。根据AMSTAR-2条目,完全符合条目16的文献最多(82.14%),其次是条目5(81.49%)、条目8(72.73%);1篇文献符合条目10(0.32%),另外条目12(68.83%)、条目13(85.39%)和条目15(67.53%)的不符合程度也相对较高。结论疾病负担系统评价/Meta分析的方法学质量有待提高,主要问题包括缺乏前期研究方案、未列出排除文献清单、异质性和偏倚风险解释不太充分等方面。仍需进一步提高系统评价方法学质量,促进循证医学的长期发展。
Objective To assess the methodological quality of systematic reviews/meta-analysis of burden of illness,analyses the factors affecting it,so as to provide a reference basis for improving the methodological quality of related studies.Methods Systematic reviews/meta-analysis of burden of illness were identified in PubMed,searching from its inception to 12 October 2024.Systematic reviews/meta-analysis of burden of illness was included,the methodological quality of the included literature was evaluated using AMSTAR-2,and data were extracted using Excel 2021.Results A total of 308 systematic reviews/meta-analysis were included,with a fluctuating upward trend in the number of publications from 2006 to 2024;of these,a total of 12 were rated as low quality.According to the AMSTAR-2 entries,the largest number of documents fully conformed to entry 16(82.14%),followed by entry 5(81.49%),and entry 8(72.73%);one document conformed to entry 10(0.32%),and relatively few conformed to entry 12(68.83%),entry 13(85.39%),and entry 15(67.53%).Conclusion The methodological quality of systematic reviews/meta-analysis of burden of illness needs to be improved,and the main problems include the lack of pre-study protocols,the absence of a list of excluded literature,and the less than adequate explanation of heterogeneity and risk of bias,etc.There is still a need to further improve the methodological quality of the systematic reviews and to promote the long-term development of evidence based medicine.
作者
梁翠
邓欣欣
崔璐
王汉彬
胡晓晔
黄家艺
杨克虎
李秀霞
LIANG Cui;DENG Xinxin;CUI Lu;WANG Hanbin;HU Xiaoye;HUANG Jiayi;YANG Kehu;LI Xiuxia(Health Technology Assessment Center/Evidence Based Social Science Research Center,School of Public Health,Lanzhou University,Lanzhou 730000,P.R.China;Evidence Based Medicine Center,School of Basic Medical Sciences,Lanzhou University,Lanzhou 730000,P.R.China;Key Laboratory of Evidence Based Medicine and Knowledge Translation of Gansu Province,Lanzhou University,Lanzhou 730000,P.R.China)
出处
《中国循证医学杂志》
北大核心
2025年第2期190-194,共5页
Chinese Journal of Evidence-based Medicine
