摘要
目的:根据孕前母体体质指数(BMI)分层分析年龄、孕期增重(GWG)及血清血脂水平与巨大儿发生的相关性。方法:回顾性分析2020年1月-2023年12月本院分娩产妇,根据孕前BMI将产妇分为BMI 18.5~24.0kg/m^(2)与24.0kg/m^(2)≤BMI<28kg/m^(2)进行分层,前者巨大儿组85例、非巨大儿组170例,后者巨大儿组141例、非巨大儿组282例。多因素logistic分析不同体质指数孕妇年龄、GWG及血脂水平与巨大儿发生的关系。结果:孕前BMI 18.5~24.0kg/m^(2)产妇组中,巨大儿组产妇年龄、GWG、血清TG水平均高于非巨大儿组(P≤0.001),而产次≥2次占比、孕前BMI、分娩孕周、血清HDL、LDL、TC水平两组无差异(P>0.05),年龄大、GWG高是巨大儿发生的独立危险因素(P<0.05),TG升高与巨大儿无独立相关性(P>0.05)。孕前24.0kg/m^(2)≤BMI<28kg/m^(2)产妇组中,巨大儿组产妇年龄、GWG、血清HDL、TC、TG水平均高于非巨大儿组(P<0.001),而产次≥2次占比、孕前BMI、分娩孕周、血清LDL水平两组无差异(P>0.05),年龄大、GWG高、TC及TG升高是巨大儿发生的独立危险因素(P<0.05)。结论:高龄、GWG过大会增加巨大儿发生风险,对于孕前超重的孕妇,血脂水平升高也是巨大儿发生危险因素。
Objective: To stratification analyze the correlation between the age, the weight gain during pregnancy(GWG), the blood lipid level of pregnant women and their macrosomia based on the pre-pregnancy body mass index(BMI) of the women. Methods: A retrospective analysis was performed on the women who had given birth from January 2020 to December 2023. According to the pre-pregnancy BMI, these women were divided into group A(women with prepregnancy BMI of 18.5kg/m^(2)-24.0kg/m^(2)) and group B(women with 24.0kg/m^(2)≤ prepregnancy BMI <28kg/m^(2). The women in group A were further divided into group A1(85 women with macrosomia) and group A1(170 women without macrosomia)), and the women in group B were further divided into group B1(141 women with macrosomia) and group B1(282 women without macrosomia). Multivariate logistic analysis was used to analyze the correlation between the age, the GWG and the blood lipid level of the women with different prepregnancy BMI and their macrosomia occurrence. Results: In group A, the age, the GWG and the serum TG level of the women in group A1 were significantly higher than those of the women in group A2(P≤0.001), while there were no significant differences in the proportion of parity ≥2 times, the prepregnancy BMI value, the gestational weeks at delivery, and the serum HDL, LDL and TC levels of the women between the two groups(P>0.05). The advanced age and the more GWG of the women were the independent risk factors of their macrosomia occurrence(P<0.05), but the increased TG level of the women had no independent correlation with their macrosomia occurrence(P>0.05). In group B, the age, the GWG and the serum HDL,TC,and TG levels of the women in group B1were significantly higher than those of the women in group B2(P<0.001),while there were no significant differences in the proportion of parity≥2time,the pre-pregnancy BMI value,the gestational weeks at delivery and the serum LDL level of the women between the two groups(P>0.05).The advanced age,the more GWG and the higher levels of TC and TG of the women were the independent risk factors of their macrosomia occurrence(P <0.05).Conclusion:The advanced age and the more GWG of the women may increase the risk of their macrosomia occurrence.For the pregnant women with overweight before pregnancy,the increased blood lipid level is also the risk factor of their macrosomia occurrence.
作者
吴永青
王家惠
WU Yongqing;WANG Jiahui(Xuancheng Central Hospital,Xuancheng,Anhui Province,242000)
出处
《中国计划生育学杂志》
2025年第2期464-467,472,共5页
Chinese Journal of Family Planning
关键词
孕前体质指数
巨大儿
年龄
孕期增重
血脂
危险因素
Pre-pregnancy body mass index
Macrosoma
Age
Gain weight during pregnancy
Blood lipids
Risk factor
