摘要
冠状动脉粥样硬化性心脏病(冠心病)目前仍是死亡率居高不下的心血管疾病,随着对其发病机制研究的深入,现在普遍认为冠脉内易损斑块与未来急性冠脉综合征的发生有关。斑块易损性主要靠血管内超声(IVUS)、光学相干断层成像(OCT)等腔内影像技术进行检查,但均需要使用额外的介入耗材,且分析时间相对较长,导致其在冠心病介入诊疗中的应用相对受限。近期有研究表明,径向壁应变(RWS)分析与经典腔内影像技术在评估易损斑块的能力上有较高一致性,且能够避免额外介入费用,有望作为评估斑块易损性的常规手段优化冠脉介入诊疗策略。本文对RWS的原理、工作流程、临床研究及现有限制作一综述。
Coronary heart disease remains one of the leading causes of cardiovascular mortality.With the in-depth understanding of the pathogenesis of coronary heart disease,it is now widely believed that vulnerable plaques within the coronary arteries are associated with the occurrence of future acute coronary syndromes.The vulnerability of plaques is mainly assessed using intravascular imaging techniques such as Intravascular Ultrasound(IVUS)and Optical Coherence Tomography(OCT).However,these methods require the use of additional interventional consumables,and the analysis is relatively time-consuming,which limits their application in the interventional diagnosis and treatment of coronary heart disease.Recent studies have shown that radial wall strain(RWS)analysis has a high consistency with traditional intravascular imaging techniques in assessing vulnerable plaques,and it can avoid additional interventional costs.RWS is expected to become a routine method for assessing plaque vulnerability and optimizing strategies for coronary intervention.This article provides a review of the principles,workflow,clinical research,and current limitations of RWS.
作者
张家珺
张海涛
苏菲菲
Zhang Jiajun;Zhang Haitao;Su Feifei(Department of Cardiology,Air Force Medical Center,People's Liberation Army,Beijing 100142,China)
出处
《中华临床医师杂志(电子版)》
2024年第7期687-691,共5页
Chinese Journal of Clinicians(Electronic Edition)
关键词
功能性血管造影
易损斑块
冠脉造影
冠心病介入
Functional angiography
Vulnerable plaque
Coronary angiography
Coronary intervention
