摘要
目的分析不同再灌注治疗的急性ST段抬高心梗患者的近期临床预后,探讨影响其预后的危险因素。方法回顾性分析354例急性ST段抬高心肌梗死患者,随机分为静脉溶栓组154例,直接PCI组200例。比较2组一般临床资料特点、住院期间梗死相关血管再通率,白细胞计数、肾小球滤过率及主要心脏事件等,用多因素分析的方法分析影响患者近期预后的危险因素。结果2组年龄、发病至入院实施治疗时间、肾小球滤过率、白细胞计数和住院期间病死率差异均无统计学意义(P>0.05),PCI组再通率高于溶栓组(P<0.05)。多因素分析表明年龄、白细胞计数升高和肾小球滤过率降低是影响患者早期死亡的危险因素。结论年龄、白细胞计数升高及肾小球滤过率降低是影响急性心梗早期死亡的危险因素,应引起重视。
Objective To investigate the main influential factors on short-term prognosis in acute myocardial infarction patients, And analyze short-term clinical outcomes after different reperfusion treatments in acute ST-segment elevation myocardial infarction patients. Methods 354 patients with ST-segment elevation myocardial infarction were enrolled and their clinical dates were analyzed retrospectively. Patients were divided into two groups ,intravenous thrombolysis group with 154 cases and direct PCI group with 200 cases. Clinical data of the general characteristics, recanalization rate of infarctrelated artery during hospitalization, white blood cell counts, glomerular filtration rate and the major cardiac events were compared between these two groups. Using multivariate analysis method, we analyze the risk factors on short-term prognosis. Results There were no significant differences of age, incidence of admission to the implementation of treatment, the mortality, as well as glomerular filtration rate and white blood cell count, during hospitalization between two groups. The recanalization rate of PCI group were significantly higher than those of thrombolysis group. Multivariate analysis showed that age, increasing white blood cell counts and lowering glomerular filtration rate in patients were all the risk factors of early death. Conclusion Age, elevated white blood cell counts and reduced glomerular filtration rate were the risk factors of early death in acute myocardial infarction patients,which should be taken more attention.
出处
《临床合理用药杂志》
2009年第19期10-11,共2页
Chinese Journal of Clinical Rational Drug Use
关键词
急性心肌梗死
再灌注治疗
Acute myocardial infarction
Reperfusion treatment
