摘要
目的 研究胸腔镜肺叶切除术患者应用地塞米松联合罗哌卡因胸椎旁阻滞的镇痛效果。方法 选择的研究对象为行胸腔镜肺叶切除术治疗患者,共计选取100例,均为2022年10月-2023年10月期间盘州市人民医院收治患者,选用随机编号法分为对照组和研究组,每组50例。对照组采用罗哌卡因,研究组采用地塞米松联合罗哌卡因胸椎旁神经阻滞。对比两组术后不同时间点静息疼痛评分(VAS)、镇痛药物使用情况、不良反应发生率及术后恢复情况。结果 术后不同时点研究组静息VAS评分均低于对照组,P<0.05。与对照组比较,研究组瑞芬太尼药物平均用量更少,术后首次按压镇痛泵时间更长,术后48 h镇痛泵有效按压次数更少,不良反应发生率更低,而术后恢复时间更短,P<0.05;结论 对胸腔镜肺叶切除患者运用地塞米松联合罗哌卡因胸椎旁神经阻滞获得的镇痛效果理想,可减少镇痛药物使用,且患者术后恢复速度快,安全性高。
Objective:Study on the analgesic effect of dexamethasone combined with ropivacaine thoracic paravertebral block in patients undergoing thoracoscopic lobectomy.Methods:The selected subjects were patients who underwent thoracoscopic lobectomy.A total of 100 patients were selected,all of whom were admitted to Panzhou People's Hospital from October 2022 to October 2023.They were randomly divided into control group and study group,with 50 patients in each group.The control group was given ropivacaine,and the study group was given dexamethasone combined with ropivacaine for thoracic paravertebral nerve block.The rest pain score(VAS),the use of analgesic drugs,the incidence of adverse reactions and postoperative recovery were compared between the two groups at different time points after operation.Results:The rest VAS scores of the study group were lower than those of the control group at different time points after operation,P<0.05.Compared with the control group,the average dosage of remifentanil in the study group was less,the time of pressing the analgesic pump for the first time after operation was longer,the effective times of pressing the analgesic pump were less at 48 hours after operation,the incidence of adverse reactions was lower,and the recovery time after operation was shorter,P<0.05.Compared with the inflammatory factors before anesthesia induction,P>0.05;Six hours after operation,the levels of IL-6 and TNF-αin the study group were lower than those in the control group,P<0.05.Conclusion:The use of dexamethasone combined with ropivacaine thoracic Used,with fast postoperative recovery,mild inflammatory response,and high safety for patients.
作者
唐心莉
曹坤英
Tang Xinli;Cao Kunying(Panzhou People's Hospital,Panzhou Guizhou 553537,China)
出处
《生命科学仪器》
2024年第5期140-142,共3页
Life Science Instruments
