摘要
目的以烯丙孕素为对象,探讨其在不同环境条件下作为饲料添加剂的崩解与溶出性能,开发适合猪场饲养需求的片剂。方法通过3因素3水平正交试验筛选处方,并对片剂的崩解时限、溶出度、外观质量等性能进行检测。结果优化后的烯丙孕素实现了7~15 min的崩解时限,优于常规片剂的2~5 min。结论优化后的烯丙孕素溶出度和含量符合标准,便于母猪摄食,能够满足猪场饲需求。
Objective To investigate the disintegration and dissolution properties of alprogesterone as a feed additive under different environmental conditions,and to develop a suitable tablet for pig farm feeding.Methods The prescription was screened by 3-factor and 3-level orthogonal test,and the disintegration time,dissolution and appearance quality of the tablets were tested.Results The disintegration time of the optimized allyl gestrel was 7~15 min,which was better than 2~5 min of conventional tablets.Conclusion The optimized dissolution and content of allyl gestrel meet the standard,which is convenient for sows to consume and can meet the feeding needs of pig farms.
作者
张晶
刘凯卫
ZHANG Jing;LIU Kai-Wei(Fujian Agricultural Products Quality and Safety Inspection and Testing Center,Fuzhou 350003,China;Famo(Fujian)Biotechnology Co.,Ltd.,Zhangzhou 363100,China)
出处
《实验室检测》
2024年第9期27-30,共4页
Laboratory Testing
关键词
烯丙孕素
溶出性能
崩解
水平正交试验
allyl gestrel
dissolution performance
disintegrate
horizontal orthogonal test
