摘要
益生菌在改善畜禽健康水平,提高生产性能,无抗绿色养殖等方面发挥重要作用。益生菌能够通过调节细胞信号因子和免疫信号通路来参与免疫调节,进而改善黏膜免疫系统的生理机能,影响宿主健康。肠道微生物区系与黏膜免疫系统联系密切,肠道和肺部通过肠-肺轴的微生物区系和免疫系统实现双向调节。益生菌在预防和治疗胃肠道及呼吸系统疾病等方面具有较大潜力。因此,对益生菌与肠道菌群、黏膜免疫调节的相互作用机制进行深入了解,有利于其在动物生产中的应用。文章对益生菌与肠道微生物区系和免疫调节的关系及益生菌对肠-肺轴的影响进行综述,以期为益生菌的深入研究和广泛应用提供参考。
Probiotics play an important role in improving the health level of livestock and poultry,improving production performance,and antibiotic-free green farming.Probiotics can participate in immune regulation by regulating cell signaling factors and immune signaling pathways,thereby improving the physiological functions of the mucosal immune system to affect the health of the host.The intestinal microbiota is closely related to the mucosal immune system,and the intestine and lungs achieve two-way regulation through the interaction of microflora and immune regulation,which is called the gut-lung axis.Probiotics have considerable potential in the prevention and treatment of gastrointestinal and respiratory diseases,so it is necessary to have an in-depth understanding of the interaction mechanism between probiotics and intestinal microbiota and mucosal immunomodulation,so as to facilitate their application in animals production.In this paper,the relationship between probiotics and intestinal microflora and immune regulation in animals and the effect of probiotics on the gut-lung axis are discussed,in order to provide reference for the in-depth research and wide application of probiotics.
作者
赵蕾蕾
魏娜
张嵘
杨小勇
董延江
吴倩
刘洋
ZHAO Lei-lei;WEI Na;ZHANG Rong;YANG Xiao-yong;DONG Yan-jiang;WU Qian;LIU Yang
出处
《饲料研究》
北大核心
2024年第22期173-178,共6页
Feed Research
基金
2022年度沈阳市科学技术计划(项目编号:22-101-0-17)。
关键词
益生菌
免疫
肠-肺轴
probiotics
immunity
gut-lung axis
