摘要
目的 分析依达拉奉联合丹红注射液对急性脑梗死患者神经功能及血清炎症因子的影响。方法 选取我院2021年7月至2023年6月期间收治的96例急性脑梗死患者为研究对象,采用随机数字表法将其分为参照组与实验组,每组48例。参照组给予依达拉奉治疗,实验组给予依达拉奉联合丹红注射液治疗。观察两组治疗前后神经功能评分以及日常活动能力、血清炎症因子、血脂水平、疗效及不良反应。结果 治疗后,实验组神经功能和日常活动能力改善效果优于参照组,且实验组血清炎症因子水平、血脂水平低于参照组,P<0.05。实验组治疗有效率95.83%,高于参照组的79.17%,P<0.05。实验组不良反应发生率8.33%,与参照组的12.50%比较,差异无统计学意义,P>0.05。结论 在急性脑梗死治疗中,依达拉奉联合丹红注射液治疗更利于挽救濒死脑细胞,改善神经功能,促进患者日常生活能力提高,同时更有助于降低炎症反应,改善血脂代谢,提高治疗有效性,且不会增加用药不良反应,具有推广价值。
Objective To analyze the effects of Edaravone combined with Danhong injection on nerve function and serum inflammatory factors in patients with acute cerebral infarction.Methods 96 patients with acute cerebral infarction admitted to our hospital from July 2021 to June 2023 were selected as the research objects,and were divided into reference group and experimental group by random number table method,with 48 cases in each group.The reference group was treated with edaravone,and the experimental group was treated with Edaravone combined with Danhong injection.Neurological function scores,daily activity ability,serum inflammatory factors,blood lipid levels,efficacy and adverse reactions were observed before and after treatment.Results After treatment,the improvement effect of nerve function and daily activity ability in experimental group was better than that in reference group,and the level of serum inflammatory factors and blood lipid in experimental group was lower than that in reference group,P<0.05.The effective rate of the experimental group was 95.83%,which was higher than that of the reference group(79.17%),P<0.05.The incidence of adverse reactions in the experimental group was 8.33%,compared with 12.50%in the reference group,there was no statistical significance(P>0.05).Conclusion In the treatment of acute cerebral infarction,Edaravone combined with Danhong injection is more conducive to saving dying brain cells,improving nerve function,promoting the improvement of patients'daily living ability,and also helps to reduce inflammation,improve lipid metabolism,improve treatment effectiveness,and does not increase adverse drug reactions,so it has the promotion value.
作者
张慧
李泉
焦恒
程玉
于龙
Zhang Hui;Li Quan;Jiao Heng;Cheng Yu;Yu Long(Shangqiu First People's Hospital,Shangqiu 476100,Henan Province,China;The First Affiliated Hospital of Zhengzhou University,Zhengzhou 450052,Henan Province,China)
出处
《罕少疾病杂志》
2025年第1期26-28,共3页
Journal of Rare and Uncommon Diseases
基金
国家自然青年科学基金项目(82001252)。
关键词
依达拉奉
丹红注射液
急性脑梗死
神经功能
血清炎症因子
血脂水平
Edaravone
Danhong Injection
Acute Cerebral Infarction
Nerve Function
Serum Inflammatory Factors
Lipid Level
