摘要
目前全球的近视率逐年上升,据估计,全球近20亿人患有近视,其中约10%为高度近视(high myopia,HM)。因其不可逆性给人们日常生活带来了严重的影响,对此进行深入的研究并采取有效的治疗显得尤为重要。HM患者并非只有眼底改变,同时也会引起中枢神经系统的改变,目前引起大脑改变主要通过多模态磁共振成像(magnetic resonance imaging,MRI)技术进行检测,常规的眼科检查和人工智能技术尚无法识别中枢神经系统的变化。为此,本文通过揭示HM引起的中枢神经系统病变,旨在提高对HM导致中枢神经系病变认识,并为未来的相关研究提供有价值的临床诊疗借鉴。
The global prevalence of myopia is increasing annually,with an estimated 2 billion people worldwide suffering from the condition,of which approximately 10%are classified as high myopia(HM).This irreversible condition poses significant challenges to daily life,highlighting the urgency of conducting in-depth research and developing effective treatments.Patients with HM not only experience changes in the retina but also alterations in the central nervous system.Currently,these brain alterations are primarily detected using multi-modal magnetic resonance imaging(MRI)technology,as conventional eye examinations and artificial intelligence technologies are insufficient for identifying changes in the central nervous system.Therefore,this study aims to elucidate the pathological changes in the central nervous system induced by HM,with the goal of enhancing understanding of HM-related central nervous system research and providing valuable insights for clinical diagnosis and treatment..
作者
周琳
柴华
袁颢钰
吴晓蓉
ZHOU Lin;CHAI Hua;YUAN Haoyu;WU Xiaorong(Department of Ophthalmology,the First Affiliated Hospital of Nanchang University,Nanchang 330006,China)
出处
《磁共振成像》
CAS
CSCD
北大核心
2024年第12期212-217,共6页
Chinese Journal of Magnetic Resonance Imaging
基金
国家自然科学基金项目(编号:8216040131、8176040196)。
关键词
病理性高度近视
中枢神经系统
磁共振成像
人工智能
结构磁共振成像
功能磁共振成像
pathological high myopia
central nervous system
magnetic resonance imaging
artificial intelligence
structural magnetic resonance imaging
functional magnetic resonance imaging
