摘要
目的:观察半夏白术天麻汤联合甲磺酸倍他司汀治疗痰浊上犯型眩晕的临床效果。方法:选取2022年6月—2023年6月铜仁市江口县人民医院收治的痰浊上犯型眩晕患者100例作为研究对象,随机分为对照组与观察组,各50例。对照组应用甲磺酸倍他司汀治疗,观察组在对照组基础上应用半夏白术天麻汤治疗。比较两组中医证候积分、治疗效果、凝血功能、不良反应。结果:治疗前,两组中医证候积分比较,差异无统计学意义(P>0.05);治疗7 d、28 d后,两组中医证候积分下降,观察组低于对照组,差异有统计学意义(P<0.05)。观察组治疗总有效率高于对照组,差异有统计学意义(P=0.013)。治疗前,两组凝血酶原时间(PT)、纤维蛋白原(Fbg)、活化部分凝血活酶时间(APTT)、凝血酶时间(TT)比较,差异无统计学意义(P>0.05);治疗后,两组PT、APTT、TT延长,Fbg水平降低,观察组优于对照组,差异有统计学意义(P<0.05)。两组不良反应总发生率比较,差异无统计学意义(P>0.05)。结论:半夏白术天麻汤联合甲磺酸倍他司汀治疗痰浊上犯型眩晕的临床效果显著,可缓解临床症状,改善凝血功能,且未增加不良反应发生风险。
Objective:To observe the clinical effect of Banxia Baizhu Tianma Decoction combined with betahistine mesylate in the treatment of phlegm turbidity-induced vertigo.Methods:A total of one hundred patients with phlegm turbid vertigo treated in Tongren Jiangkou County People's Hospital from June 2022 to June 2023 were selected as the study objects and randomly divided into control group and observation group,with fifty cases in each group.The control group was treated with betahistine mesylate,and the observation group was treated with Banxia Baizhu Tianma Decoction on the basis of control group.TCM syndrome score,therapeutic effect,coagulation function and adverse reactions were compared between the two groups.Results:Before treatment,there was no significant difference in TCM syndrome scores between the two groups(P>0.05);after 7 and 28 days of treatment,the scores of TCM symptoms of the two groups decreased,and the observation group was lower than the control group,the difference was statistically significant(P<0.05).The total effective rate of the observation group was higher than that of the control group,the difference was statistically significant(P=0.013).Before treatment,there was no significant difference in prothrombin time(PT),fibrinogen(Fbg),activated partial thromboplastin time(APTT)and thrombin time(TT)between the two groups(P>0.05);after treatment,PT,APTT and TT were prolonged and Fbg levels were decreased in both groups,and the observation group was better than the control group,the difference was statistically significant(P<0.05).There was no significant difference in the total incidence of adverse reactions between the two groups(P>0.05).Conclusion:Banxia Baizhu Tianma Decoction combined with betahistine mesylate has a remarkable clinical effect in the treatment of phlegm turbidity-induced vertigo,which can alleviate clinical symptoms and improve coagulation function without increasing the risk of adverse reactions.
作者
李发良
Li Faliang(Tongren Jiangkou County People's Hospital,Tongren 554400,Guizhou Province,China)
出处
《中外医药研究》
2024年第13期105-107,共3页
JOURNAL OF CHINESE AND FOREIGN MEDICINE AND PHARMACY RESEARCH
关键词
眩晕
痰浊上犯型
半夏白术天麻汤
甲磺酸倍他司汀
Vertigo
Pattern of phlegm turbidness
Banxia Baizhu Tianma Decoction
Betahistine mesylate
