摘要
目的回顾性分析无锡地区2021年1月—2023年11月成人感染肺炎支原体对抗菌药物的敏感性,为临床用药提供参考依据。方法回顾性分析2021年1月—2023年11月来上海交通大学医学院附属瑞金医院无锡分院就诊患者呼吸道感染的104株肺炎支原体,对14种常见抗菌药物的耐药性。结果104株肺炎支原体中,耐乙酰螺旋霉素57株(54.8%),耐莫西沙星45株(43.3%),耐强力霉素34株(32.7%),耐美满霉素26株(25.0%),耐环丙沙星16株(15.4%),耐克林霉素14株(13.5%);耐依托红霉素、加替沙星、交沙霉素、左氧氟沙星、阿奇霉素、克拉霉素、红霉素及罗红霉素均在9株以下。结论对成人呼吸道感染的肺炎支原体,临床应以大环内酯类和喹诺酮类抗菌药物进行治疗,但应避免使用大环内酯类中的乙酰螺旋霉素和喹诺酮类中的莫西沙星和环丙沙星。
Objective To retrospectively analyze drug resistance of Mycoplasma pneumonia in adults with respiratory tract infections in Wuxi region from January 2021 to November 2023,and provide information for infection therapy.Methods Drug resistance of 104 strains of mycoplasma pneumonia from the respiratory tract of adult patients to 14 antimicrobial drugs used for treatment was retrospectively analyzed from January 2021 to November 2023 in Wuxi Branch,Ruijin Hospital,Shanghai Jiao Tong University School of Medicine.Results Mycoplasma pneumonia showed a high rate of resistance to some of the commonly prescribed antimicrobial drugs:acetylspiramycin(54.8%,57 strains),moxifloxacin(43.3%,45 strains),doxycycline(32.7%,34 strains),minocycline(25.0%,26 strains),ciprofloxacin(15.4%,16 strains),clindamycin l(13.5%,14 strains),a low rate of resistance to other commonly prescribed antimicrobial drugs such as erythromycin,gatifloxacin,josamycin,levofloxacin,azithromycin,clarithromycin,erythromycin,and roxithromycin(less than 9 strains).Conclusion Respiratory tract infections with Mycoplasma pneumoniae in adult should be treated with macrolides and quinolones,but but acetylspiramycin(a macrolide)and moxifloxacin and ciprofloxacin(quinolones)should be avoided.
作者
翟培珺
许敏凡
李悦铭
王宏
刘曾
李小奇
丁熠熠
ZHAI Peijun;XU Minfan;LI Yueming;WANG Hong;LIU Zeng;LI Xiaoqi;DING Yiyi(Department of Clinical Laboratory,Wuxi Branch,Ruijin Hospital,Shanghai Jiao Tong University School of Medicine,Wuxi Jiangsu 214000,China)
出处
《中国卫生标准管理》
2024年第11期95-98,共4页
China Health Standard Management
关键词
肺炎支原体
呼吸道感染
抗菌药物
药敏分析
大环内酯
喹诺酮
mycoplasma pneumoniae
respiratory infection
antimicrobial drugs
drug resistance
macrolide
quinolone
