胰岛素一次性冲击治疗糖尿病酮症酸中毒患者的临床疗效及对患者血糖水平的影响被引量：10

Clinical Efficacy of Insulin One-time Shock Treatment for Patients with Diabetic Ketoacidosis and Its Effect on Patients'Blood Glucose Levels

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摘要目的分析胰岛素一次性冲击对糖尿病酮症酸中毒(Dibetic Ketocidosis,DKA)的作用。方法回顾性选取2022年6月—2023年9月陆军第七十三集团军医院收治的98例DKA患者的临床资料,根据治疗方式的不同分为两组,各49例。对照组给予传统治疗,研究组给予胰岛素一次性静脉冲击治疗。对比两组症状缓解时间、血糖达标时间、血糖指标、不良反应发生情况。结果研究组症状缓解时间、血糖达标时间均短于对照组,差异有统计学意义(P均<0.05)。治疗后,研究组糖化血红蛋白为(6.15±0.34)%,空腹血糖为(7.13±0.93)mmol/L,餐后2 h血糖为(8.16±1.26)mmol/L,均低于对照组,差异有统计学意义(t=4.736、3.116、2.463,P均<0.05)。两组不良反应总发生率比较,差异无统计学意义(P>0.05)。结论胰岛素一次性冲击治疗DKA,能够提高疗效,降低血糖水平,且不会增加不良反应。 Objective To analyze the effect of insulin one-time shock on diabetic ketoacidosis(DKA).Methods The clinical data of 98 DKA patients admitted to Army 73rd Group Military Hospital from June 2022 to September 2023 were retrospectively selected and divided into two groups according to different treatment methods,with 49 cases each.The control group was given traditional treatment,and the study group was given insulin one-time intravenous shock therapy.The time of symptom relief,the time of blood glucose attainment,blood glucose index and the occur-rence of adverse reactions were compared between the two groups.Results The time of symptom relief and blood glu-cose attainment in the study group were shorter than those in the control group,and the differences were statistically significant(both P<0.05).After treatment,the glycated hemoglobin A1c of the study group was(6.15±0.34)%,the fast-ing blood glucose was(7.13±0.93)mmol/L,and the 2-hour postprandial blood glucose was(8.16±1.26)mmol/L,all of which were lower than those of the control group,and the differences were statistically significant(t=4.736,3.116,2.463,all P<0.05).There was no significant difference in the total incidence of adverse reactions between the two groups(P>0.05).Conclusion Insulin one-time shock treatment for DKA can improve the efficacy and reduce the blood glucose level without increasing the adverse reactions.

作者梁圆圆张珍林凤琴 LIANG Yuanyuan;ZHANG Zhen;LIN Fengqin(Army 73rd Group Military Hospital,Xiamen,Fujian Province,361000 China)

机构地区陆军第七十三集团军医院

出处《糖尿病新世界》 2024年第7期187-190,共4页 Diabetes New World Magazine

关键词胰岛素一次性糖尿病酮症酸中毒疗效血糖水平 Insulin One-time Diabetes mellitus Ketoacidosis Efficacy Blood glucose level

分类号 R587.2 [医药卫生—内分泌]