摘要
目的 :观察琼玉膏对实验性肺癌小鼠化疗导致的骨髓抑制的影响。方法 :使用癌细胞接种的方法制造肺癌模型 ,分别观测空白对照组 (生理盐水 )、化疗组 (顺氨氯铂 )及联合组 (顺氨氯铂加琼玉膏 )小鼠的血常规及骨髓有核细胞计数变化。结果 :联合组及对照组的外周血红细胞、白细胞及血小板皆明显高于化疗组 (P<0 .0 1)。化疗组骨髓有核细胞数明显低于联合组与对照组 (P<0 .0 1)。而联合组与对照组相比 ,对照组又高于联合组 (P <0 .0 5 )。结论
Objective:The effects of Qiongyugao on the bone marrow inhibition of lung cancer mice treated by chemotherapy Methods:Use GLC 82 lung adenocarcinoma cells to transplant to the axillary region of C57/BL mice to make models The models were divided into three groups,chemotherapy group,chemotherapy plus qiong yugao group(treating group),and control group The blood routine and bone marrow nucleated cells of three groups were tested respectively Results:For chemotherapy group,after treatment,the blood routine were markedly decreased(P<0 01),comparing with control group and treating group But there was no statistics differences between control group and treating group(P>0 05) The bone marrow nucleated cells number were markedly decreased(P<0 01),comparing between control and treating group,the number was higher in control group(P<0 05) Conclusion:Qiongyugao can lighten the bone marrow inhibition caused by chemotherapy
出处
《山东中医杂志》
北大核心
2002年第12期736-738,共3页
Shandong Journal of Traditional Chinese Medicine
基金
广东省中医药管理局基金项目 (编号 10 2 0 44 )
关键词
琼玉膏
肺癌
化疗
血常规
骨髓有核细胞计数
qiongyugao
lung cancer
chemotherapy
blood routine
bone marrow nucleated cells number
