摘要
目的探讨多模态超声诊断侵袭性前列腺癌的临床应用价值。方法选取并分析60例前列腺癌患者资料,根据病理Gleason评分分组:评分>4+3为高侵袭组,评分≤4+3为低中侵袭组。两组患者均行常规超声检查、实时剪切波弹性成像与超声造影检查,比较两组常规超声征象、实时剪切波弹性成像参数值与超声造影参数;用受试者工作特征曲线(ROC)分析各检查方式对前列腺癌侵袭性的诊断价值。结果低中侵袭组常规超声检查阴性征象百分比高于高侵袭组;阳性征象中高侵袭组弥漫性的百分比高于低中侵袭组,差异有统计学意义(P<0.05)。低中侵袭组平均值(Emean)、最大值(Emax)低于高侵袭组,差异有统计学意义(P<0.05)。低中侵袭组初始强度(B)、峰值强度(PI)低于高侵袭组(P<0.05),两组达峰时间(TTP)、峰值减半时间(T_(1/2))比较差异无统计学意义(P>0.05)。ROC分析结果显示,常规超声、剪切波弹性成像、超声造影单独及联合检查的AUC分别为0.683、0.717、0.750、0.833,三者联合应用的诊断价值较高。结论多模态超声检查对侵袭性前列腺癌具有较高诊断价值,可指导临床选择合适的治疗方案。
Objective To study the value of multimodal ultrasound in diagnosis of invasive prostate cancer.Methods The data of 60 patients with prostate cancer were analyzed retrospectively.Patients were divided into two groups according to the pathological Gleason score,high invasion group(Gleason score>4+3)and low-to-medium invasion group(Gleason score≤4+3).Conventional ultrasound,shear wave elastography(SWE)and contrast-enhanced ultrasound were performed in both groups.Receiver operating characteristic(ROC)curve was plotted to evaluate the value of the above examinations in diagnosing the invasive prostate cancer.Results The proportion of negative signs of conventional ultrasound in low-medium invasion group was higher than that in high invasion group,and the proportion rate of positive signs in high invasion group was higher than that in low and middle invasion group(P<0.05).The mean(EMean)and maximum(EMax)of SWE elasticity of low-medium invasion group were lower than those of high invasion group(P<0.05).The basic intensity(BI)and peak intensity(PI)of low-medium invasion group were lower than those of high invasion group(P<0.05).The time to peak(TTP)and time to half relaxation(T_(1/2))yielded no statistical difference between two groups(P>0.05).ROC analysis showed that the AUCs of conventional ultrasound,shear wave elastography,contrast-enhanced ultrasound and combination examination were 0.683,0.717,0.750,and 0.833,respectively,indicating that the combined application of three examinations obtained the highest diagnostic value.Conclusion Multimodal ultrasound has a high diagnostic value for invasive prostate cancer,which can be used clinically to guide the selection of appropriate treatment options.
作者
刘辉
高曼丽
叶新华
周琦
王南
包迪
张惠敏
张楠
LIU Hui;GAO Manli;YE Xinhua;ZHOU Qi;WANG Nan;BAO Di;ZHANG Huimin;ZHANG Nan(Department of Ultrasound,Suqian First People's Hospital,Suqian 223800,China)
出处
《医学影像学杂志》
2023年第8期1415-1418,共4页
Journal of Medical Imaging
基金
江苏省宿迁市科技计划资助项目(编号:S202114)。
关键词
前列腺癌
多模态超声检查
剪切波弹性成像
超声造影
Prestatic cancer
Multimodal ultrasound
Shear wave elastography
Contrast-enhanced ultrasound
