摘要
目的研究新型冠状病毒肺炎患者伴发抑郁焦虑症状的影响因素。方法选择新型冠状病毒肺炎患者143例,采用汉密尔顿抑郁量表(HAMA)、汉密尔顿抑郁量表(HAMD)分组,用t检验与卡方检验对抑郁、焦虑组和无抑郁、无焦虑组的性别、年龄、性格、婚姻状况、职业、受教育年限、居住地、家庭月收入、淋巴细胞数量、C反应蛋白、D-二聚体、血沉进行对比分析;采用二元Logistic回归分析新冠肺炎伴发抑郁焦虑影响因素。结果新型冠状病毒肺炎合并焦虑、合并抑郁发生率为22.38%、19.58%,焦虑组性格内向、无固定职业、家庭月收入<5000元和D-二聚体占比均高于无焦虑组(P<0.05)。抑郁组淋巴细胞数量、C反应蛋白、D-二聚体、性格内向、无固定职业、家庭月收入<5000元占比均高于无抑郁组(P<0.05)。回归分析结果显示,性格内向、D-二聚体升高是发生焦虑的危险因素(P<0.05);家庭月收入≥5000元、有固定职业是发生焦虑的保护因素(P<0.05)。性格为内向、D-二聚体、淋巴细胞数量、C反应蛋白是发生抑郁的危险因素(P<0.05);有固定职业、家庭月收入≥5000元是发生抑郁的保护因素(P<0.05)。结论新型冠状病毒肺炎伴发焦虑抑郁症状的风险因素是性格内向和D-二聚体、淋巴细胞数量、C反应蛋白升高,保护因素是高家庭收入及有固定职业。可以提前预测焦虑抑郁发生的可能性,提高治疗效果和改善恢复预后。
Objective To explore the influence factors for concomitant depressive anxiety symptoms in patients with Corona Virus Disease 2019(COVID-19).Methods 143 patients with COVID-19 were selected and divided into two groups according to Hamilton Anxiety Scale(HAMA)and Hamilton Depression Scale(HAMD).T-test and chi square test were used to compare genders,ages,characteristics,marital status,occupations,years of education,residences,monthly household incomes,lymphocyte numbers,C-reactive protein levels,D-dimer levels and erythrocyte sedimentation rates between depression,anxiety groups and non-depression,non-anxiety groups;binary logistic regression was used to analyze the influencing factors of depression and anxiety in patients with COVID-19.Results The incidence rates of anxiety and depression in patients with COVID-19 were 22.38%and 19.58%respectively.The anxiety group showed more introversion,higher D-dimer level,tended to have no fixed occupation and monthly household income<5000 yuan than non-anxiety group(P<0.05).The depression group showed more introversion and higher lymphocyte levels,higher C-reactive protein levels,higher D-dimer levels,tended to have no fixed occupation and monthly household income<5000 yuan than non-depression group(P<0.05).Regression analysis showed that introversion and elevated D-dimer were risk factors for anxiety(P<0.05),and monthly household income≥5000 yuan and fixed occupation were protective factors for anxiety(P<0.05).Introversion,elevated D-dimer,lymphocyte and C-reactive protein were risk factors for depression(P<0.05),and having a fixed occupation and monthly household income≥5000 yuan were protective factors for depression(P<0.05).Conclusion The risk factors for COVID-19 with anxiety and depression symptoms are introversion,elevated D-dimer,lymphocyte number and C-reactive protein,and the protective factors are higher family incomes and fixed occupation.To predict the possibilities of anxiety and depression in advance may help improve the treatment effect and recovery prognosis.
作者
杨洛宁
范玉兰
孙仕田
YANG Luoning;FAN Yulan;SUN Shitian(Linyi Mental Health Center,Linyi 276005,China)
出处
《精神医学杂志》
2022年第6期620-624,共5页
Journal of Psychiatry
基金
临沂市科技发展计划项目(编号:202120022)。
