摘要
目的分析卵磷脂络合碘片联合氨碘肽注射液在玻璃体混浊中的应用价值及安全性。方法选取我院2021年1月~2023年1月收治的70例玻璃体混浊患者,根据随机数表法分为对照组(35例,48眼)和研究组(35例,54眼)。对照组进行氨碘肽注射液治疗,研究组在对照组的基础上进行卵磷脂络合碘片治疗。对比两组患者主要症状消失时间、玻璃体混浊评分、镇痛效果(VAS)评分、生活质量评分、不良反应、临床疗效。结果研究组眼睛干涩、视物模糊、玻璃体出血等症状消失时间均显著低于对照组;治疗后,研究组玻璃体混浊评分、VAS评分均低于对照组;研究组生活质量评分高于对照组;较对照组各项指标比,研究组的不良反应发生率处于更低水平,治疗有效率处于更高水平,P<0.05,提示数据差异在统计学方面具有显著性。结论给予玻璃体混浊患者卵磷脂络合碘片联合氨碘肽注射液治疗,能够有效推进症状消失时间、改善玻璃体混浊、缓解镇痛效果、提高生活质量、降低不良反应发生情况,安全性较好,值得在临床推广应用。
Objective To analyze the application value and safety of lecithin complex iodine tablets combined with amiodopeptide injection in vitreous turbidity.Methods Seventy patients with vitreous opacity admitted to our hospital from January 2021 to January 2023 were selected and divided into control group(35 cases,48 eyes)and study group(35 cases,54 eyes)according to random number table method.The control group was treated with aminoiodopeptide injection,and the study group was treated with lecithin complex iodine tablets on the basis of the control group.Duration of main symptoms,vitreous opacity score,analgesic effect(VAS)score,quality of life score,adverse reactions and clinical efficacy were compared between the two groups.Results The disappearance time of symptoms such as dry eyes,blurred vision and vitreous hemorrhage in the study group was significantly lower than that in the control group.After treatment,vitreous turbidity score and VAS score of the study group were lower than those of the control group.The quality of life score of the study group was higher than that of the control group.Compared with the control group,the incidence of adverse reactions of the study group was at a lower level and the effective rate of treatment was at a higher level(P<0.05),indicating that the data differences were statistically significant.Conclusion The treatment of lecithin complex iodine tablets combined with amiodopeptide injection in patients with vitreous turbidity can effectively promote the time of symptom disappearance,improve vitreous turbidity,alleviate analgesic effect,improve quality of life,and reduce the occurrence of adverse reactions.It is safe and worthy of clinical application.
作者
闫俊茹
毛小慧
YAN Jun-ru;MAO Xiao-hui(Zhumadian ophthalmology hospital,ophthalmology,Zhumadian 463000,Henan Province,China;Hangzhou Gongshu District Changqing Chaoming neighbourhood community health service center,General outpatient,Hangzhou 310005,Zhejiang Province,China)
出处
《罕少疾病杂志》
2023年第7期20-22,共3页
Journal of Rare and Uncommon Diseases
基金
河南省中医药科学研究专项课题(2019JDZX2100)。
关键词
玻璃体混浊
卵磷脂络合碘片
氨碘肽注射液
生活质量
Vitreous Opacity
Lecithin Complexing Iodine Tablets
Aminoiodopeptide Injection
Quality of Life
