摘要
目的:探究学龄期急性腹泻患儿细菌、病毒病原学临床特点,旨在为学龄期急性腹泻患儿合理治疗方案制订提供参考。方法:选取2020年6-12月上饶市人民医院收治的67例学龄期急性腹泻患儿为对象,由迪安检测中心进行病原菌、病毒(轮状病毒、诺如病毒、星状病毒及人腺病毒等)的病原学检测,同时结合患儿疾病信息进行病原谱流行规律分析。结果:67例学龄期急性腹泻发病无明显性别、年龄、季节等分布特征,2例同时感染细菌与病毒,细菌感染率为56.52%,略高于病毒感染的43.48%。细菌类型以沙门菌(35.90%)、致病性大肠埃希菌(28.21%)为主,病毒感染类型以轮状病毒(46.67%)、诺如病毒(23.33%)较常见,学龄期急性腹泻患儿病原体感染类型的性别、年龄、发病季节等分布差异均无统计学意义(P>0.05)。学龄期急性腹泻患儿主要致病菌沙门菌、致病性大肠埃希菌对氨苄西林耐药率均高于71.00%,且沙门菌对头孢他啶、复方磺胺甲噁唑片耐药率高于78.00%,此外,致病性大肠埃希菌对环丙沙星、复方磺胺甲噁唑片耐药性均为45.45%。结论:学龄期急性腹泻患儿常见感染源为细菌(沙门菌、致病性大肠埃希菌为主)和病毒(轮状病毒、诺如病毒为主),学龄期急性腹泻无明显的流行特征,临床需积极监测患儿病原学特点,对于合理用药和病情控制有重要指导意义。
Objective:To explore the etiological characteristics of bacteria and viruses in school-age children with acute diarrhea,so as to provide reference for developing reasonable treatment plan for this group.Method:Sixty-seven school-age children with acute diarrhea admitted to the Shangrao People's Hospital were selected as the research subjects from June to December 2020.Etiological detection of pathogenic bacteria and viruses(rotavirus,norovirus,astrovirus and human adenovirus)were carried out at Dean Testing Center for inspection and testing.At the same time,the epidemic law of pathogen spectrum was analyze combined with the children's disease information.Result:There was no significant difference in the distribution of gender,age or season among the subjects.There were 2 cases infected with both bacteria and virus.The bacterial infection rate(56.52%)was slightly higher than the viral infection rate(43.48%).Bacteria mainly included Salmonella(35.90%)and Pathogenic Escherichia Coli(28.21%),while viruses mainly included rotavirus(46.67%)and norovirus(23.33%).There were no significant differences in the type of pathogen infection in terms of gender,age or season of onset(P>0.05).The resistance rates of Salmonella and Pathogenic Escherichia Coli to Ampicillin were higher than 71.00%,and the resistance rates of Salmonella to Ceftazidime and Compound Sulfamethoxazole Tablets were higher than 78.00%.Besides,the resistance rate of Pathogenic Escherichia Coli to Ciprofloxacin and Compound Sulfamethoxazole Tablets was all 45.45%.Conclusion:The common pathogenic factors of school-age children with acute diarrhea are bacteria(mainly Salmonella,Pathogenic Escherichia Coli)and viruses(mainly rotavirus,norovirus),but there are no epidemiological characteristics.Clinically,the etiological characteristics of school-age children with acute diarrhea should be monitored actively,which is of great guiding significance for rational drug use and disease control.
作者
毛高峰
MAO Gaofeng(Shangrao People's Hospital,Jiangxi Province,Shangrao 334000,China)
出处
《中国医学创新》
CAS
2023年第13期74-77,共4页
Medical Innovation of China
关键词
急性腹泻
学龄期
细菌
病毒
病原学
Acute diarrhea
School-age
Bacteria
Virus
Etiology
