摘要
目的探究双相Ⅰ型障碍躁狂患者认知功能与冲动性的关系。方法方便选取2019年3月—2021年3月茂名市第三人民医院收治的双相Ⅰ型障碍躁狂患者82例为研究组,另选取同期心理测试健康的体检人群82名为对照组。分别采用重复性成套神经心理状态测验(RBANS)及汉化版Barratt-11冲动性量表(BIS-11)对两组的认知功能与冲动性进行评价,并采用Pearson相关性分析来分析两者之间的关系。结果研究组RBANS量表中视觉广度评分为(82.08±8.28)分、即刻记忆评分为(75.14±5.34)分、延时记忆评分为(81.76±5.57)分、注意力评分为(86.33±6.37)分、言语功能评分为(86.52±4.76)分,对照组分别为(91.83±9.11)分、(87.92±6.25)分、(92.04±7.64)分、(96.89±6.52)分、(91.36±5.58)分,研究组5个维度评分均低于对照组,差异有统计学意义(t=7.172、14.078、9.846、10.491、5.976,P<0.001)。研究组BIS-11量表中运动冲动性、无计划冲动性以及认知冲动性评分均高于对照组,差异有统计学意义(t=14.472、18.435、16.792,P<0.001);Pearson相关性分析结果显示,RBANS量表中注意力及言语功能与BIS-11量表中运动冲动性呈负相关(r=-0.284,P=0.045;r=-0.356,P=0.028);RBANS量表中视觉广度、注意力与BIS-11量表中无计划冲动性呈负相关(r=-0.279,P=0.047;r=-0.319,P=0.025);RBANS量表中即刻记忆、延时记忆及言语功能与BIS-11量表中认知冲动性呈负相关(r=-0.326,P=0.017;r=-0.297,P=0.006;r=-0.359,P=0.002)。结论双相Ⅰ型障碍躁狂患者存在一定的认知功能损害,冲动性处于较高水平,其冲动性与认知功能呈负相关关系。
Objective To explore the relationship between cognitive function and impulsivity in manic patients with bi⁃polarⅠdisorder.Methods A total of 82 patients with bipolarⅠdisorder who were admitted to Maoming Third People′s Hospital from March 2019 to March 2021 were conveniently selected as the study group.In addition,82 healthy physical examinations were selected as the control group during the same period.The cognitive function and impulsivity of the two groups were evaluated by the repetitive neuropsychological state test(RBANS)and the Chinese version of Barratt-11 Impulsivity Scale(BIS-11),and the relationship between them was analyzed by Pearson correla⁃tion analysis.Results In the RBANS scale of the study group,the visual span score was(82.08±8.28)points,the imme⁃diate memory score was(75.14±5.34)points,the delayed memory score was(81.76±5.57)points,and the attention score was(86.33±6.37)points,speech function score(86.52±4.76)points,and the control group′s RBANS scores were(91.83±9.11)points,(87.92±6.25)points,(92.04±7.64)points,(96.89±6.52)points,and(91.36±5.58)points,the scores of five dimensions in the study group were lower than those in the control group,and the difference was statisti⁃cally significant(t=7.172,14.078,9.846,10.491,5.976,P<0.001).The scores of motor impulsivity,unplanned impul⁃sivity and cognitive impulsivity in the BIS-11 scale of the study group were all higher than those of the control group,and the differences were statistically significant(t=14.472,18.435,16.792,P<0.001).The results of Pearson correla⁃tion analysis showed that attention and speech function in RBANS scale were negatively correlated with motor impul⁃sivity in BIS-11 scale(r=-0.284,P=0.045;r=-0.356,P=0.028);visual span and attention in the RBANS scale were negatively correlated with unplanned impulsivity in the BIS-11 scale(r=-0.279,P=0.047;r=-0.319,P=0.025);imme⁃diate memory,delayed memory and speech funtion in RBANS scale were negatively correlated with cognitive impulsiv⁃ity in BIS-11 scale(r=-0.326,P=0.017;r=-0.297,P=0.006;r=-0.359,P=0.002).Conclusion Mania patients with bi⁃polarⅠdisorder have certain cognitive impairment,impulsiveness is at a high level,and its impulsiveness is nega⁃tively correlated with cognitive function.
作者
张春锋
邓金勇
高建箱
ZHANG Chunfeng;DENG Jinyong;GAO Jianxiang(Outpatient Department,Maoming Third People′s Hospital,Maoming,Guangdong Province,525000 China;Depart-ment of Medicine and Education,Maoming Third People′s Hospital,Maoming,Guangdong Province,525000 China)
出处
《中外医疗》
2022年第29期10-13,19,共5页
China & Foreign Medical Treatment
关键词
双相Ⅰ型障碍
认知功能
冲动性
躁狂
BipolarⅠdisorder
Cognitive function
Impulsivity
Mania
