摘要
综述毛发分段检验在法庭毒物学中的应用进展,为毛发检材的精细化检验和纵深解析提供理论技术参考。结合近年来文献报道,论述毛发分段检验新技术和检验结果解析的应用案例。毛发分段分析能够获得药物和毒物在毛发生长方向上的时间-空间分布信息,除传统的平行分割检验外,跟踪采样分析、微分段分析、质谱成像分析等方法也日益普及,并成功应用于毒物摄入时间推断、戒毒评价、毛发样本污染判别、药物-毛发结合机制研究等。毛发分段检验能够为吸贩毒、麻醉侵害等案件的调查鉴定提供有力的毒理学证据,未来将在法医毒物检验领域发挥更积极作用。
This review aims to summarize the application of hair segmentation analysis in forensic toxicology, and to provide theoretical and technical reference for fine inspection and in-depth explanation of hair samples. Combined with the recent literatures, new techniques of hair segmentation analysis and the application cases of detection result explanations were discussed. The temporal and spatial distribution information of drugs and toxicants along the hair growth direction could be obtained by hair segmentation analysis. In addition to the traditionally used parallel cut analysis, the applications of tracking sampling analysis, micro-segmentation analysis, mass spectrometry imaging analysis and other methods are increasingly widely used, and have been successfully applied on the estimation of poison intake time, detoxification assessment, contamination identification of hair samples, drug-hair binding mechanism research, etc. Hair segmentation analysis can provide strong toxicological evidence for the investigation and identification of the cases of drug abuse and trafficking, anesthesia rapes and others, and will play more active roles in forensic toxicology.
作者
邹波
常靖
王爱华
张云峰
于忠山
Zou Bo;Chang Jing;Wang Aihua;Zhang Yunfeng;Yu Zhongshan(Institute of Forensic Science,Ministry of Public Security&Beijing Engineering Research Center of Crime Scene Evidence Examination,Beijing 100038,China)
出处
《中国法医学杂志》
CSCD
2022年第6期584-588,共5页
Chinese Journal of Forensic Medicine
基金
公安部鉴定中心基本科研业务费项目(2020JB010)。
关键词
毛发
分段检验
法庭毒物学
研究进展
Hair
Segmentation analysis
Forensic toxicology
Research progress
