摘要
目的探讨颈椎前路椎间盘切除植骨融合术中应用3D打印多孔钛合金椎间融合器治疗颈椎病的临床疗效与安全性。方法纳入自2018-06—2020-06行颈椎前路椎间盘切除植骨融合术治疗的67例颈椎病,按随机数字表法分为试验组(33例)与对照组(34例),试验组术中置入3D打印多孔钛合金椎间融合器,对照组置入聚醚醚酮椎间融合器。比较两组手术时间、术中出血量、颈椎JOA评分、颈椎矢状位参数(融合节段高度和C_(2~7)Cobb角)、椎间融合情况。结果两组手术均顺利完成,切口均一期愈合,随访时间为(14.6±4.2)个月,期间均无明显并发症发生。两组手术时间、术中出血量、术后6个月颈椎JOA评分比较差异无统计学意义(P>0.05)。两组术后1周的融合节段高度、C_(2~7)Cobb角比较差异无统计学意义(P>0.05),试验组术后3个月及术后6个月的融合节段高度、C_(2~7)Cobb角高于对照组,差异有统计学意义(P<0.05)。试验组术后3个月椎间融合率高于对照组,差异有统计学意义(χ^(2)=4.586,P=0.032);两组术后6个月椎间融合率比较差异无统计学意义(χ^(2)=0.447,P=0.504)。结论颈椎前路椎间盘切除植骨融合术中应用3D打印多孔钛合金椎间融合器可减缓椎体沉降、维持颈椎的生理曲度、加速椎间融合,疗效满意。
Objective To explore clinical efficacy and safety of 3D print porous titanium alloy intervertebral fusion cage in an-terior cervical discectomy and bone graft fusion for treatment of cervical spondylopathy.Methods A total of 67 patients withcervical spondylopathy who underwent anterior cervical discectomy and bone graft fusion from June 2018 to June 2020 were in-cluded and assigned into experiment group(n=33)and control group(n=34),by a random number table.3D print porous titani-um alloy lumbar fusion cage was implanted in experiment group while PEEK lumbar fusion cage was implanted in control group.Duration of surgery,intraoperative blood loss,cervical JOA score,cervical sagittal parameters(height of fusion segment,C_(2-7)Cobb angle),intervertebral fusion were compared between two groups.Results All surgeries were successful performed andall incisions healed primarily.Mean time of follow up was 14.6±4.2 months(12-20 months).No significant complications oc-curred.Between the two groups,duration of surgery,intraoperative blood loss and cervical JOA score 6 moths after surgery werenot significantly different(P>0.05);Height of fusion segment and C_(2-7)Cobb angle one week after surgery were not significantlydifferent(P>0.05).Both height of fusion segment and C_(2-7)Cobb angle 3 months and 6 months after surgery in experiment groupwere significantly higher than those in control group(P<0.05).Intervertebral fusion rate 3 months after surgery in experimentgroup was significantly higher than that in control group(χ^(2)=4.586,P=0.032).Intervertebral fusion rate 6 months after surgeryin experiment group was not significantly different from that in control group(χ^(2)=0.447,P=0.504).Conclusion Use of 3Dcage in anterior cervical discectomy and bone graft fusion can slow down subsidence of the vertebral body,maintain physiologi-cal curvature of cervical spine and accelerate intervertebral fusion.The efficacy is satisfactory.
作者
王彦金
周英杰
王寅
郝宇鹏
张博文
WANG Yan-jin;ZHOU Ying-jie;WANG Yin;HAO Yu-peng;ZHANG Bo-wen(No.2 Department of Spinal Surgery,Luoyang Orthopedic-Traumatological Hospital of Henan Province(Henan Provincial Orthopedic Hospital),Luoyang,Henan 471002,China;不详)
出处
《中国骨与关节损伤杂志》
2023年第1期1-5,共5页
Chinese Journal of Bone and Joint Injury
基金
中医药传承与创新人才工程(仲景工程)
河南省科技攻关计划项目(182102310678)。
