摘要
基因编辑因其“精确性、易用性、低成本”的技术优势掀起了全世界的研究热潮。尤其是2013年CRISPR技术的诞生,带动基因编辑飞速发展,已广泛应用于医学、农业、工业、环境等领域,也引发了一系列关于安全及伦理风险的讨论,其中“自上而下”的监管将发挥重要作用。本文概述了近年来基因编辑技术的应用进展和问题探讨,从人类、植物、动物基因编辑三方面出发,重点梳理了国际及我国的基因编辑监管现状,并对我国的基因编辑监管提供咨询参考建议。
Gene editing has aroused a worldwide research upsurge for the advantages of accuracy,usability,and low cost.The birth of CRISPR technology in 2013 drove the rapid development of gene editing,which has been widely used in medicine,agriculture,industry,environment and so on,and also triggered a series of discussions on safety and ethical risks.“Top-down”supervision plays an important role.Focusing on human,plant and animal gene editing,in this paper we summarize the application progress and problem discussion of gene editing technology,comb the current situation of gene editing supervision in China and abroad,and propose some suggestions on supervision.
作者
张丽雯
刘加兰
王洪
于建荣
ZHANG Li-Wen;LIU Jia-Lan;WANG Hong;YU Jian-Rong(Shanghai Information Center for Life Sciences,Shanghai Institute of Nutrition and Health,Chinese Academy of Sciences,Shanghai 200031,China;Kunming Institute of Zoology,Chinese Academy of Sciences,Kunming 650201,China;University of Chinese Academy of Sciences,Beijing 100049,China)
出处
《生命科学》
CSCD
北大核心
2022年第10期1317-1326,共10页
Chinese Bulletin of Life Sciences
关键词
基因编辑
应用
风险
监管
gene editing
application
risk
supervision