摘要
目的:评价浅层X射线治疗顽固性寻常疣的疗效和不良反应。方法:回顾性分析29例应用浅层X线照射治疗的顽固性寻常疣患者,治疗1~2次,第一次照射剂量8 Gy,4周后复诊,如皮疹仍然未愈,再次照射8 Gy。结果:29例患者共有54处皮疹,第一次治疗后,29处皮疹完全消退,疣体消退率53.7%,10例患者痊愈,痊愈率34.5%。第二次对17例患者的21处疣体进行治疗,14处疣体消退,消退率66.7%,11例患者痊愈,痊愈率64.7%。最终共有27例患者完成疗程,21例患者痊愈,痊愈率77.8%.50处疣体,43处疣体消退,消退率86%。不良反应主要为一过性放射性皮炎,第一次和第二次治疗后分别有3例和5例发生,均在3个月内消失。结论:浅层X线放射对于顽固性寻常疣具有较好的疗效,为临床治疗提供了新的选择。
Objective:To evaluate the efficacy of superficial X-ray in the treatment of refractory verruca vulgaris.Methods:29 patients with refractory verruca vulgaris were treated with superficial X-ray irradiation,1-2 times,the first dose of 8Gy,if the rash still did not heal 4 weeks later,then given the second X-ray irradiation with dose of 8Gy.Results:There were 54 rashes in 29 patients.After the first treatment,29 rashes were completely resolved,with a regression rate of 53.7%.10 patients were cured,with a recovery rate of 34.5%.After the second treatment,14 of the 21 warts retreated,with a regression rate of 66.7%.Of the 17 patients,11 were cured,with a recovery rate of 64.7%.In the end,27 patients completed the whole observation,and 21 patients were cured,with a recovery rate of 77.8%.There were 50 warts in total,and 43 warts retreated,with a regression rate of 86%.The main adverse reactions were transient radiation dermatitis,which occurred in 3 cases after the first treatment and 5 cases after the second treatment,and disappeared within 3 months.Conclusion:Superficial X-ray radiation has a good effect on refractory viral wart,providing a new choice for treatment.
作者
单晓峰
刘鑫洲
李建可
王秀环
刘国艳
张福仁
SHAN Xiaofeng;LIU Xinzhou;LI Jianke;WANG Xiuhuan;LIU Guoyan;ZHANG Furen(Shandong Provincial Hospital for Skin Diseases&Shandong Provincial Institute of Dermatology and Venereology,Shandong First Medical University&Shandong Academy of Medical Sciences,Jinan 250022,China)
出处
《中国麻风皮肤病杂志》
2023年第2期86-88,共3页
China Journal of Leprosy and Skin Diseases
关键词
浅层X线
人类乳头瘤病毒
疣
superficial X-ray
human papillomavirus
wart
