摘要
细胞因子有“细胞之间沟通语言”之称,它参与着机体器官组织的生理与病理过程。对细胞因子与眼部疾病的相关研究,不仅可以揭示其发病的分子机制,监测细胞因子的指标还可用于疾病诊断、预判疾病的转归、明确疾病干预的时机并有助于制定新型靶向治疗的策略。本文中笔者就细胞因子概念与研究的溯源及其在糖尿病性眼病、视网膜静脉阻塞、年龄相关性黄斑变性、自身免疫性葡萄膜炎、青光眼性视神经病变、增殖性玻璃体视网膜病变及早产儿视网膜病变等眼部疾病中的研究进展进行综述。
Cytokines,known as"communication language between cells",are involved in the physiological and pathological processes of tissues and body organs.Investigating cytokines and eye diseases can not only reveal the molecular mechanism of their pathogenesis,but also monitor the indicators of cytokines,which can also be used to make the diagnosis,predict the outcome of the disease,clarify the timing of disease intervention,and help to formulate new targeted treatment strategies.The concept and research origin of cytokines about eye diseases such as diabetes ophthalmopathy,retinal vein occlusion,age-related macular degeneration,autoimmune uveitis,glaucomatous optic neuropathy,proliferative vitreoretino-pathy and retinopathy of prematurity were reviewed in this study.
作者
李坚
陶勇
郦舒伊
张小花
胡勇平
Jian Li;Yong Tao;Shuyi Li;Xiaohua Zhang;Yongping Hu(Department of Ophthalmology,Affiliated Hangzhou First People′s Hospital,Zhejiang University School of Medicine,Hangzhou 310006,China;Department of Ophthalmology,Beijing Chaoyang Hospital,Capital Medical University,Beijing 100020,China)
出处
《中华眼科医学杂志（电子版）》
2022年第2期115-119,共5页
Chinese Journal of Ophthalmologic Medicine(Electronic Edition)
基金
国家自然科学基金面上基金项目(82070948)。
关键词
细胞因子
眼部疾病
分子机制
Cytokines
Eye diseases
Molecular mechanism
