摘要
目的采用Meta分析系统评价临床实践中运用养血清脑颗粒治疗高血压头痛的疗效性及安全性。方法检索CNKI、PubMed、维普、万方数据库,收集2001-2020年关于养血清脑颗粒治疗高血压头痛的文献,应用Review Mananger 5.3进行数据分析。结果纳入11篇文献,数据分析后提示养血清脑颗粒可有效缓解高血压头痛(RR=1.52,95%CI 1.41~1.64,P<0.00001),无明显不良反应。结论临床中应用养血清脑颗粒针对高血压头痛有明显疗效且副作用小,并阐述其发病机制可能与脑血管痉挛有关,因存在纳入文献质量不高、样本量较小等不足,还需更多的RCT验证。
Objective Meta analysis system was used to evaluate the efficacy and safety of nourish serum brain granules in the treatment of hypertensive headache in clinical practice.Methods Searching CNKI,PubMed,Weipu and Wanfang databases,collecting literature from 2001 to 2020 on the treatment of nourish serum brain granules for hypertension and headache,and applying Review Mananger 5.3 for data analysis.Results In 11 articles,it was suggested that nourish serum brain granules could effectively relieve hypertensive headache after data analysis(RR=1.52,95%CI 1.41~1.64,P<0.00001),without obvious adverse reactions.Conclusion The clinical application of nourish serum brain granules for hypertension headache has obvious efficacy and less side effects,and explains that its pathogenesis may be related to cerebrovascular spasm,due to the lack of high quality of the included literature and small sample size,more RCT validation is needed.
作者
李倩倩
杨园园
曹锦江
袁有才
LI Qianqian;YANG Yuanyuan;GAO Jinjiang(Shanxi University of Chinese Medicine,Xianyang 712046,China)
出处
《中风与神经疾病杂志》
CAS
2022年第11期1004-1007,共4页
Journal of Apoplexy and Nervous Diseases
关键词
高血压头痛
脑血管痉挛
META分析
Hypertension and headache
Cerebrovascular spasm
Meta-analysis
