摘要
目的运用meta分析系统评价针刀治疗膝骨关节炎(KOA)的临床疗效。方法计算机检索CNKI、万方、PubMed、Web of Science、Embase等数据库,搜集针刀治疗KOA的临床随机对照试验(RCT),检索日期为建库至2021年4月,采用RevMan 5.4软件对结局指标进行meta分析。结果纳入16项研究,共1321例患者。meta分析结果显示针刀组在提升总有效率、Lysholm膝关节评分(LKS),降低视觉模拟疼痛评分(VAS)、西安大略和麦克马斯特大学骨关节炎指数评分量表(WOMAC)、牛津大学膝关节评分(OKS),降低肿瘤坏死因子-α(TNF-α)水平等方面发挥更显著的作用,差异有统计学意义(P<0.05)。结论针刀在改善KOA临床症状、保护膝关节软骨、恢复膝关节功能方面具有一定优势,可在临床推广。
Objective To systematically evaluate the clinical efficacy of acupotomy on knee osteoarthritis(KOA)using meta-analysis.Methods The databases such as CNKI,Wanfang,PubMed,Web of Science,and Embase were searched by computer to collect the clinical randomized controlled trials(RCT)of acupotomy on KOA.The retrieval date was from the establishment of these databases to April 2021.Meta-analysis was performed on outcome indices using RevMan 5.4 software.Results A total of 16 studies and 1321 patients were included.Meta-analysis showed that the acupotomy group played a more significant role in improving the total effective rate and lysholm knee joint score(LKS),and reducing visual analog pain score(VAS),Western Ontario and Mcmaster University osteoarthritis index scale(WOMAC),oxford university knee joint score(OKS)and reduced tumor necrosis factor-α(TNF-α)level,with statistically significant differences(P<0.05).Conclusion Acupotomy has certain advantages in improving clinical symptoms of KOA,protecting the knee cartilage,recovering the knee function,which can be promoted in clinical practice.
作者
周艳玲
朱俊琛
王超
刘奇奇
ZHOU Yanling;ZHU Junchen;WANG Chao;LIU Qiqi(Graduate School,Anhui University of Chinese Medicine,Anhui,Hefei 230031,China;The Second Affiliated Hospital of Anhui University of Chinese Medicine,Anhui,Hefei 230038,China)
出处
《中国医药科学》
2022年第19期122-126,共5页
China Medicine And Pharmacy
基金
安徽省“十三五”医疗卫生重点专科项目(卫科教秘〔2017〕529号)。
