摘要
目的研究未成熟血小板分数(IPF)、高荧光未成熟血小板比例(H-IPF)指标在血流感染中的早期诊断价值。方法选取2020年7月—2021年1月广州市第一人民医院的血培养阳性患者100例作为主要的研究对象,重症病人对照50例,健康对照50例。收集各组患者IPF、H-IPF、大型血小板比率(P-LCR)、血小板体积分布宽度(PDW)、粒/淋、粒/单指标的数值,采用单因素方差分析、构建ROC曲线的方法分析比较各组的IPF、H-IPF、P-LCR、PDW、粒/淋、粒/单比值的差异及其与血流感染效能的关系。结果IPF、H-IPF、粒/淋、粒/单比值在血流感染组高于其他2组,差异有统计学意义(χ^(2)分别是15.190,10.250,39.490,12.850;P<0.05),而P-LCR、PDW在3组之间无统计学意义。其中,IPF与H-IPF对血流感染诊断效能较高,其中IPF的AUC为0.855(95%CI为0.737~0.973),H-IPF的AUC为0.845(95%CI为0.722~0.968)。结论IPF、H-IPF与血流感染密切相关,这2个指标对血流感染患者具有一定的诊断价值。
Objective To explore the early diagnosis value of immature platelet fraction(IPF)and high fluorescent immature platelet fraction(H-IPF)in bloodstream infection.Methods A total of 100 patients with positive blood culture result from July 2020 to January 2021 in Guangzhou First People s Hospital were selected as the research objects,in the mean while,50 critically ill patients and 50 healthy patients were enrolled as two control groups.The values of IPF,H-IPF,platelet-large cell rate(P-LCR),platelet distribution width(PDW),neutrophils/lymphocytes,neutrophils/monocyte ratio of patients in each group were collected,and one-way analysis of variance and ROC curve were used to compare the data,to further analyze their relationship with the bloodstream infection.Results The IPF,H-IPF,neutrophils/lymphocytes,neutrophils/monocyte ratio in the bloodstream infection group were significantly higher than control groups,with statistical significance(χ^(2)=15.190,10.250,39.490,12.850;P<0.05),while P-LCR and PDW had no statistical significance.Among them,IPF and H-IPF were highly effective in diagnosing bloodstream infection,the AUC of IPF was 0.855(95%CI:0.737-0.973)and the AUC of H-IPF was 0.845(95%CI:0.722-0.968).Conclusions IPF and H-IPF were closely related to bloodstream infection,and these two indicators had a certain value in diagnosing patients with bloodstream infection.
作者
罗丽香
熊德芳
杨潇
徐邦牢
LUO Lixiang;XIONG Defang;YANG Xiao;XU Banglao(Guangzhou First People s Hospital,Guangzhou 510180,China;Guangzhou Chest Hospital,Guangzhou 510095,China)
出处
《广州医药》
2022年第6期36-41,共6页
Guangzhou Medical Journal
