摘要
目的了解血清炎性指标对血流感染患者感染病原菌的早期鉴别诊断的价值。方法采用回顾性分析的方法对本院2014年10月至2015年9月住院患者血培养阳性确诊血流感染的60例患者,根据血培养病原菌不同分为革兰阴性菌组与革兰阳性菌组,分析两组早期的血白细胞(WBC)、血小板(PLT)、C反应蛋白(CRP)、降钙素原(PCT)、白细胞介素-6(IL-6)水平,比较两组间的差异。结果革兰阴性菌组与革兰阳性菌组在发病早期,WBC、PLT、CRP、PCT、IL-6均有不同程度的的改变,但PLT的差异具有统计学意义(P<0.05),余差异无统计学意义(P>0.05)。结论 PLT定量检测可以作为早期鉴别革兰阴性菌与革兰阳性菌血流感染的快速诊断手段,为早期的抗感染方案的制订提供有效、可行的实验室依据。
Objective To study the early differential diagnosis value of serum inflammatory markers in the pathogenic bacteria of patients with bloodstream infection.Methods 60 specimens with blood positive culture from patients with bloodstream infection from 2015 October to 2014 September were analyzed retrospectively.Gram negative bacteria group and gram positive bacteria group were divided according to the different pathogenic bacteria in blood culture,two groups of early white blood cells（WBC）,platelet（PLT）,C-reactive protein（CRP）,procalctionin（PCT）,interleukin 6（IL-6）concentration of the two groups were compared.Results There were different degrees changes of CRP,PLT,PCT,IL-6and WBC in the early stage of Gram negative bacteria group and Gram positive bacteria group bloodstream infection.There was significant difference in blood PLT（P〈0.05）,others indicater had no statistical significance chagnes（P〉0.05）.Conclusion Quantitative detection of PLT can be used as a quick diagnostic method for early identification of gram negative bacteria and gram positive bacteria bloodstream infection,which could provide effective and feasible laboratory basis for making early anti-infection therapeutic scheme.
出处
《国际检验医学杂志》
CAS
2016年第10期1373-1374,共2页
International Journal of Laboratory Medicine
关键词
血清炎性指标
血流感染
病原菌
血小板
诊断
serum inflammatory markers
bloodstream infection
pathogenic bacteria
platelet
diagnosis
