摘要
目的探讨不同时机应用卡前列素氨丁三醇对阴道分娩后存在宫缩乏力性产后出血倾向产妇的影响。方法选取2020年10月至2021年10月福建省龙岩市第一医院收治的86例阴道分娩后存在宫缩乏力性产后出血倾向产妇作为研究对象,按照随机数字表法将其分为对照组(n=43)和观察组(n=43)。对照组于产妇出血量达到200 ml时采用卡前列素氨丁三醇治疗,观察组于胎儿娩出后即刻采用卡前列素氨丁三醇治疗,比较两组产妇的产后出血情况、子宫宫底高度、住院时间以及不良反应发生率。结果观察组产妇用药15 min、用药30 min、产后2 h、产后24 h后的产后出血量均少于对照组,且组内不同时间节点比较,差异有统计学意义(P<0.05);观察组产妇的产后出血率(9.30%)低于对照组(30.23%),差异有统计学意义(P<0.05);观察组产妇产后2、24、72、120 h的子宫宫底高度均低于对照组,且组内不同时间节点比较,差异有统计学意义(P<0.05);观察组产妇的住院时间短于对照组,差异有统计学意义(P<0.05);观察组产妇的不良反应总发生率(4.66%)低于对照组(20.93%),差异有统计学意义(P<0.05)。结论对于阴道分娩后存在宫缩乏力性产后出血倾向的产妇,在胎儿娩出后即刻予以卡前列素氨丁三醇治疗可有效减少产后出血量,降低产后出血率,加速子宫复旧,缩短住院时间,且不良反应发生率更低。
Objective To investigate the influence of Carboprost Tromethamine at different timings on puerperae with uterine atony and postpartum hemorrhage tendency after vaginal delivery.Methods From October 2020 to October 2021,86 puerperae with uterine atony and postpartum hemorrhage tendency after vaginal delivery who were admitted to the First Hospital of Longyan City in Fujian Province were selected as the research objects,and they were divided into the control group(n=43)and the observation group(n=43)according to the random number table method.The control group was treated with Carboprost Tromethamine when the maternal bleeding volume reached 200 ml.The observation group was treated with Carboprost Tromethamine immediately after the fetus was delivered.Postpartum hemorrhage,uterine fundus height and the incidence of adverse reactions were compared between the two groups.Results The amount of postpartum hemorrhage in the observation group after medication for 15 minutes,medication for 30 minutes,2 hours postpartum,and 24 hours postpartum were less than those in the control group,and the differences at different time points in the group were statistically significant(P<0.05).The postpartum hemorrhage rate in the observation group(9.30%)was lower than that in the control group(30.23%),and the difference was statistically significant(P<0.05).The uterine fundus height of the observation group at 2,24,72,120 h postpartum were lower than those of the control group,and the differences at different time points in the group were statistically significant(P<0.05).The hospitalization time of the observation group was shorter than that of the control group,and the difference was statistically significant(P<0.05).The total incidence of maternal adverse reactions in the observation group(4.66%)was lower than that in the control group(20.93%),and the difference was statistically significant(P<0.05).Conclusion For parturient with uterine atony and postpartum hemorrhage tendency after vaginal delivery,Carboprost Tromethamine can effectively reduce postpartum hemorrhage,reduce postpartum hemorrhage rate,accelerate uterine involution,shorten hospitalization time,and the incidence of adverse reactions is lower.
作者
钟凌丽
黄敏红
黄娇英
ZHONG Lingli;HUANG Minhong;HUANG Jiaoying(Department of Obstetrics,the First Hospital of Longyan City in Fujian Province,Fujian Province,Longyan 364000,China;Department of Ultrasound,the Second Hospital of Longyan City in Fujian Province,Fujian Province,Longyan 364000,China)
出处
《中国当代医药》
CAS
2022年第32期116-119,共4页
China Modern Medicine
关键词
卡前列素氨丁三醇
阴道分娩
宫缩乏力
产后出血
用药时机
Carboprost Tromethamine
Vaginal delivery
Uterine atony
Postpartum hemorrhage
Medication timing