摘要
随着我国养犬数量的升高,肿瘤性疾病已严重威胁到犬的生命健康安全。乳腺癌是最常见的母犬肿瘤性疾病,对无法直接切除或已转移的恶性肿瘤常采用化学疗法与手术疗法进行联合治疗。紫杉醇是从红豆杉树皮中提取分离的四环二萜类有机化合物,属于抗微管蛋白类药物,因其特殊的抗癌机制被广泛应用于癌症的临床研究。为推广紫杉醇在犬乳腺癌治疗中的应用,文章对紫杉醇在犬乳腺肿瘤疾病中的研究进展进行总结,旨为紫杉醇对犬乳腺癌的临床治疗提供新思路。
With the increase of the number of dogs in China in recent years, tumor diseases have seriously threatened the life and health of dogs. Breast cancer is the most common tumor disease in female dogs. Chemotherapy and surgery are often used to treat malignant tumors that cannot be directly resected or have metastasized. Paclitaxel is a tetracyclic diterpenoid organic compound extracted from the bark of Taxus chinensis. It belongs to the anti tubulin drugs and is widely used in the clinical research of cancer due to its special anti-cancer mechanism. In order to promote the application of paclitaxel in the treatment of canine breast cancer, this paper summarizes the research progress of paclitaxel in canine breast cancer disease, aiming to provide a new idea for the clinical treatment of canine breast cancer with paclitaxel.
作者
张茹梦
ZHANG Rumeng(Hebei Agricultural University,Baoding,Hebei 071000)
出处
《中兽医学杂志》
2022年第10期85-87,共3页
Chinese Journal of Traditional Veterinary Science
关键词
紫杉醇
化疗
犬
乳腺肿瘤
Taxol
Chemotherapy
Dog
Breast tumor
