摘要
慢性阻塞性肺疾病(chronic obstructive pulmonary disease,COPD)和非小细胞肺癌(non-small cell lung cancer,NSCLC)是两种在我国发病率较高的疾病,给我国医疗事业带来沉重的负担,因两者具有共同致病危险因素,例如吸烟、气道慢性反应炎症、氧化应激、免疫调节异常等,研究两者之间的机制及治疗策略具有重要的临床意义。与之相关的研究更新频率较快,因此该文对近年来发表的最新研究文献与观点进行了综述,主要目的是讨论COPD进展为肺癌的机制,以及合并这两种疾病的患者其治疗策略的进展。
Chronic obstructive pulmonary disease(COPD)and non-small cell lung cancer(NSCLC)are two kinds of diseases with high incidence in China,which bring a heavy burden to China's medical industry.Because they have common pathogenic risk factors,such as smoking,chronic airway inflammation,oxidative stress,abnormal immune regulation,etc.It is of great clinical significance to study the mechanism and treatment strategy of COPD and lung cancer.The related research updates rapidly,so this paper reviews the latest research literature and views published in recent years,and the main purpose is to discuss the mechanism of COPD progressing into lung cancer,and the progress of treatment strategies for patients with these two diseases.
作者
杨贤洲
王初旭
赵军
YANG Xian-zhou;WANG Chu-xu;ZHAO Jun(Department of Thoracic Surgery,the First Affiliated Hospital of Soochow University,Suzhou,Jiangsu,215006,China)
出处
《中国血液流变学杂志》
CAS
2022年第2期328-332,共5页
Chinese Journal of Hemorheology
基金
苏州市卫生计生委科技项目(LCZX201902)。
关键词
慢性阻塞性肺疾病
治疗
肺癌
机制
chronic obstructive pulmonary disease
treatment
lung cancer
mechanism
