摘要
本研究筛选了11项采用功能性磁共振成像技术探究言语自闭症人群词义加工的研究,探讨了该人群与典型人群脑激活模式的差异是否具有跨研究的稳定性。结果表明,差异的脑激活模式稳定存在,且表现为主要涉及左额上回的典型脑区激活不足。该结果为言语ASD人群语言加工的神经机制提供了来自词义加工的跨研究激活证据,在明确“减弱的额叶激活”这一稳定差异表现的基础上,强调了针对不同语言加工任务开展元分析研究的必要性。
The current study identified 11 published journal articles that used fMRI to investigate lexical-semantic processing in individuals with ASD.Activation likelihood estimation analysis was adopted to investigate whether atypical brain activation patterns in individuals with ASD were stable across studies and how the atypical performance manifested.The results revealed that although the ASD group activated typical lexical-semantics processing brain regions,differential brain activation patterns were steadily present between the ASD and TD groups,manifested as hypoactivation in the left superior frontal gyrus in the ASD group.These findings provided evidence for the atypical brain responses to lexical-semantics processing in individuals with ASD from a cross-study perspective.Their atypical brain activation activities when processing meanings of words were consistent with the"decreased frontal lobe activation"hypothesis.The current study highlighted that distinguishing between different levels of language processing can help researchers identify the corresponding neural markers of certain types of language impairments in autistic populations.
作者
俞稼钰
靳羽西
梁丹丹
YU Jiayu;JIN Yuxi;LIANG Dandan(Department of Chinese and Bilingual Studies,The Hong Kong Polytechnic University,Hong Kong 999077,China;School of Chinese Language and Culture,Nanjing Normal University,Nanjing 210097,China;Interdisciplinary Research Center for Linguistic Science,University of Science and Technology of China,Hefei 230026,China)
出处
《心理科学进展》
CSSCI
CSCD
北大核心
2022年第11期2448-2460,共13页
Advances in Psychological Science
关键词
自闭症谱系障碍
词义
FMRI
元分析
Autism Spectrum Disorder
lexical-semantic
fMRI
meta-analysis
