摘要
目的:了解宁夏回族自治区(宁夏)布鲁氏菌病(布病)流行病学特征及趋势变化,为布病防治策略制定和重点区域识别提供参考依据。方法:自"中国疾病预防控制信息系统传染病监测报告系统"收集2004-2019年宁夏布病报告病例数据,采用描述性流行病学方法分析病例三间分布情况(时间、人群、地区分布)。结果:2004-2019年宁夏共报告人间布病病例15337例,死亡病例1例;年均发病率为15.21/10万,范围为0.02/10万~44.83/10万,不同年份间发病率比较,差异有统计学意义(χ^(2)=14731.60,P<0.001)。其中,2004-2010年处于低发态势,年均发病率为1.32/10万;2011-2019年进入高发阶段,年均发病率为24.83/10万。布病在全年各月均有发病,发病时间主要集中在3-9月,占71.60%(10981/15337);4-8月季节指数均>100%,存在明显季节性;发病年龄主要集中在20~<70岁,占89.60%(13742/15337);男性明显多于女性,性别比为2.66∶1.00(11141∶4196);职业以农牧民为主,占86.03%(13194/15337)。自2014年开始全区22个县(区、市)均有布病病例报告,且均为重度流行区;发病率在前3位的县(区)分别为盐池县(103.73/10万)、红寺堡区(56.01/10万)、同心县(29.18/10万),不同地区间比较差异有统计学意义(χ^(2)=3.80,P<0.001)。结论:宁夏布病发病率呈上升趋势,疫情形势严峻。建议在布病高发地区有针对性地开展积极有效的干预措施,遏制布病进一步传播蔓延。
Objective To learn about the epidemiological characteristics and trends of brucellosis in Ningxia Hui Autonomous Region(Ningxia),and to provide reference for formulation of brucellosis prevention strategies and identification of key areas.Methods The case data from 2004 to 2019 were collected from the"China Disease Prevention and Control Information System Infectious Disease Monitoring and Reporting System",and descriptive epidemiological methods were used to analyze the distribution of cases(time,population,and regional distribution).Results From 2004 to 2019,a total of 15337 human brucellosis cases and 1 death case were reported in Ningxia.The average annual incidence rate was 15.21/100000,ranging from 0.02/100000 to 44.83/100000.The difference in incidence rate in different years was statistically significant(χ^(2)=14731.60,P<0.001).Among them,from 2004 to 2010,the incidence rate was low,with an average annual incidence rate of 1.32/100000;from 2011 to 2019,it entered a high incidence stage,with an average annual incidence rate of 24.83/100000.Brucellosis occured in every month of the year,and the onset time was mainly in March to September,accounting for 71.60%(10981/15337);seasonal indexes from April to August was all>100%,with obvious seasonality.The age of onset mainly concentrated in 20-<70 years old,accounting for 89.60%(13742/15337);males were significantly more than females,with a sex ratio of 2.66∶1.00(11141/4196);the occupations were mainly farmers and herdsmen,accounting for 86.03%(13194/15337).Since 2014,cases had been reported in 22 counties(districts,cities)in the region,all of which were all severely endemic areas;the top three counties(districts)with incidence rate were Yanchi County(103.73/100000),Hongsibao District(56.01/100000)and Tongxin County(29.18/100000),respectively,the difference between different regions was statistically significant(χ^(2)=3.80,P<0.001).Conclusions The incidence rate of brucellosis in Ningxia is on the rise,and the epidemic situation is severe.It is recommended to carry out active and effective intervention measures in areas with high incidence of brucellosis to curb the further spread of brucellosis.
作者
段红菊
吴向林
马天波
孙军玲
齐蓉婷
闫芳
Duan Hongju;Wu Xianglin;Ma Tianbo;Sun Junling;Qi Rongting;Yan Fang(Department of Parastitic Diseases and Brucellosis Control,Ningxia Center for Disease Control and Prevention,Yinchuan 750004,China;Deparment of Infections Disease Managment,Chinese Center for Disease Control and Prevention,Beijing 102206,China)
出处
《中华地方病学杂志》
CAS
北大核心
2022年第7期580-584,共5页
Chinese Journal of Endemiology
基金
宁夏自然科学基金(2022A1721)。
关键词
布鲁氏菌病
流行病学特征
疫情分析
Brucellosis
Epidemiological characteristics
Epidemic analysis
