摘要
目的 探讨腹腔镜手术对良性卵巢肿瘤患者应激反应与卵巢功能的影响。方法 选取2019年3月至2020年8月间陕西中医药大学第二附属医院收治的行手术治疗的90例良性卵巢肿瘤患者作为研究对象,根据手术方式的差异,将接受开腹手术的45例患者纳入对照组,接受腹腔镜手术的45例患者纳入观察组。对两组患者手术前后应激反应与卵巢功能变化情况进行分析比较。结果 术前,两组患者卵巢功能与应激反应指标比较,差异无统计学意义(P>0.05)。术后3d,观察组黄体生成素、卵泡刺激素、皮质醇、胰高血糖素和β-内啡肽含量均低于对照组,雌二醇含量高于对照组,差异均有统计学意义(均P<0.05)。结论 腹腔镜手术可以有效减少手术创伤,减轻应激反应,对卵巢功能影响较小,有利于术后康复。
Objective To investigate the effects of laparoscopic surgery on stress response and ovarian function in patients with benign ovarian tumors. Methods Ninety patients with benign ovarian tumors who received surgical treatment were selected at Second Affiliated Hospital of Shaanxi University of Chinese Medicine from March 2019 to August 2020. According to the difference of surgical methods, 45 patients who underwent laparoscopic surgery were included in an observation group, and 45 patients who underwent laparotomy were included in a control group. The changes in stress response and ovarian function were analyzed and compared between the two groups before and after operation. Results There were no significant differences in ovarian function and stress response indexes between the two groups before surgery(P>0.05). At 3 d after the operation, the levels of luteinizing hormone(LH), follicle stimulating hormone(FSH), cortisol(COR), glucagon and β-endorphin were significantly lower in the observation group than in the control group(all P<0.05), and the level of estradiol(E;) was significantly higher in the study group than in the control group(all P<0.05). Conclusion Laparoscopic surgery can effectively reduce surgical trauma, relieve stress response in patients with benign ovarian tumors with less effect on ovarian function, which is beneficial to postoperative recovery of patients.
作者
李晓娟
王蓓蓓
LI Xiao-juan;WANG Bei-bei(Third Department of Gynaecology,Second Affiliated Hospital of Shaanxi University of Chinese Medicine,Xianyang 712000,China;First Department of Gynaecology,Shaanxi University of Chinese Medicine Affliated Hospital,Xianyang 712000,China)
出处
《中国肿瘤临床与康复》
2022年第6期681-683,共3页
Chinese Journal of Clinical Oncology and Rehabilitation
关键词
腹腔镜
良性卵巢肿瘤
开腹手术
应激反应
卵巢功能
Laparoscopy
Benign ovarian tumors
Laparotomy
Stress response
Ovarian function
