摘要
以氯化胆碱-尿素-1,4-丁二醇组成的低共熔溶剂(DES)为提取溶剂,采用超声辅助法提取绵马贯众中的总间苯三酚类成分,考察含水量、液料比、提取时间对绵马贯众中总间苯三酚类成分提取的影响。结果表明,最佳提取条件为:DES含水量62%,液料比16∶1 mL/g,提取时间60 min时,总间苯三酚得率可达18.59%。
The deep eutectic solvent(DES)consisting of choline chloride,carbamide and 1,4-butylene glycol was used as extraction solvent,ultrasound-assisted method was used to extract phloroglucinol derivatives from Dryopteridis Crassirhizomatis Rhizoma.Box-Behnken response surface methodology was used to investigate the effects of water ratio,liquid-solid ratio and extraction time on the yield of phloroglucinol derivatives.The results showed that the optimum extraction conditions were as follows:DES water ratio 62%,liquid-solid ratio 16∶1 mL/g,and extraction time 60 min.Under these conditions,the yield of phloroglucinol derivatives was 18.59%.
作者
赵晋彤
阚晶晶
季宇彬
ZHAO Jin-tong;KAN Jing-jing;JI Yu-bin(College of Pharmacy,Harbin University of Commerce,Harbin 150076,China;Postdoctoral Station on Chinese Materia Medica of Harbin University of Commerce,Harbin 150076,China)
出处
《应用化工》
CAS
CSCD
北大核心
2022年第5期1373-1376,共4页
Applied Chemical Industry
基金
黑龙江省博士后基金(LBH-Z17097)
黑龙江省普通高等学校青年创新人才培养计划项目(UNPYSCT-2020221)
哈尔滨商业大学博士启动基金项目(15KJ19)。
关键词
绵马贯众
间苯三酚类成分
低共熔溶剂
响应面分析法
Dryopteridis Crassirhizomatis Rhizoma
phloroglucinol derivatives
deep eutectic solvent
response surface method
