摘要
目的:探讨行为奖励干预(CM)技术对合并滥用苯丙胺类药的美沙酮维持治疗(MMT)者的作用。方法:以抽签法将合并使用苯丙胺类药的55例MMT者随机分为干预组(30例)和对照组(25例)。对照组仅给予常规的MMT,干预组则给予6个月的CM与MMT。分别在干预3个月末、6个月末检测两组的脱失率、尿检阳性率及服药率,使用Barratt冲动量表(BIS-11)评估其冲动性。结果:干预3及6个月末,干预组脱失率、尿检阳性率明显低于对照组,服药率明显高于对照组(P均<0.05)。两组受试者在3个月、6个月时的BIS-11总分及各分量表的得分与基线比较及两组间比较,差异无统计学意义(P>0.05)。结论:CM技术可增加合并滥用苯丙胺类药的MMT者的疗效及治疗依从性,但对冲动性无改善作用。
Objective:To explore the positive effects of contingency management(CM)on patients with methadone maintenance treatment(MMT)combined with amphetamines abuse.Method:Fifty-five MMT patients were randomized into intervention group(n=30)and control group(n=25)by means of the draw.The control group received routine MMT,and the intervention group received 6 months of CM and MMT.At the end of 3 months and 6 months,the rates of deletion,urine test positive and medicine taking were evaluated and the impulsivity was also evaluated with Barratt Impulsiveness Scale(BIS-11)in the two groups.Results:Compared with the control group,the intervention group had less drop out rate,less positive rate of urine test and increasing rate of medicine taking at the end of 3 and 6 months(all P<0.05).There were no significant differences in each subscales score and total score of BIS-11 compared to base line in the two groups and between the groups(P>0.05).Conclusion:For MMT patients abusing amphetamines,CM can enhance the curative effect of MMT and increase the treatment adherence,howerver,CM don't improve impulsivity.
作者
刘悦
陈为升
沈雯雯
李龙辉
赖苗军
谢小虎
徐泽民
刘惠芬
周文华
LIU Yue;CHEN Wei-sheng;SHEN Wen-wen;LI Long-hui;LAI Miao-jun;XIE Xiao-hu;XU Ze-min;LIU Hui-fen;ZHOU Wen-hua(Ningbo Kangning Hospital,Ningbo 315201,China)
出处
《临床精神医学杂志》
CAS
2022年第3期180-184,共5页
Journal of Clinical Psychiatry
基金
宁波市自然科学基金资助项目(2019A610296)。
关键词
美沙酮维持治疗
苯丙胺类药
行为奖励干预
methadone maintenance treatment
amphetamines
contingency-management
