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双柏散治疗血循毒蛇咬伤的临床疗效观察 被引量:4

The clinical efficacy of Shuangbai San on venomous snake bite
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摘要 目的:探讨外敷双柏散治疗血循毒蛇咬伤的临床疗效。方法:纳入2017年1月-2019年12月广州中西医结合医院收治的60例血循毒蛇咬伤患者为对象,按照随机数字表法分为两组,各30例,其中对照组给予常规西医治疗,观察组在对照组基础上外敷双柏散进行治疗。分析两组临床疗效,记录治疗前后疼痛视觉模拟评分法评分及患肢肿胀程度,并观察治疗期间不良反应发生情况。结果:观察组治疗后总有效率显著高于对照组,差异有统计学意义(P<0.05)。两组治疗后3 d疼痛评分及患肢肿胀程度较治疗前显著降低(P<0.05),两组治疗后10 d上述指标较治疗前、治疗后3 d显著降低(P<0.05);观察组治疗后3 d、5 d上述指标显著低于对照组(P<0.05)。观察组治疗期间不良反应发生率低于对照组,但差异无统计学意义(P>0.05)。结论:在血循毒蛇咬伤常规治疗基础上外敷双柏散可明显改善患者的局部疼痛症状,促进患肢消肿,提高临床疗效,且安全性较高。 Objective:To investigate the clinical efficacy of external application with Shuangbai San(双柏散)on blood circulation venomous snake bite.Methods:A total of 60 cases from January 2017 to December 2019 were enrolled and divided into two groups according to the random number table method,with 30 cases in each group.The control group was given routine Western medicine,and the observation group was given external application with Shuangbai San.Results:The total efficiency in the observation group was significantly higher than that in the control group,and the difference was statistically significant(P<0.05).3 days after treatment in the two groups,the pain score and swelling degree of the affected limb were significantly lower than those before treatment(P<0.05).10 days after treatment in the two groups,the above indexes were significantly lower than those before treatment and 3 days after treatment(P<0.05).3 days and 5 days after treatment in the observation group,the above indicators were significantly lower than the control group(P<0.05).The incidence of adverse reactions in the observation group during treatment was lower than the control group,but there was no statistically significant difference between the two groups(P>0.05).Conclusion:Routine Western medicine plus external application with Shuangbai San on venomous snake bite can significantly ameliorate local pain symptoms,promote the reduction of swelling of the affected limb,and improve the clinical efficacy,with high safety.
作者 马清龄 曾燕青 陈洋凯 MA Qingling
出处 《中医临床研究》 2022年第8期121-123,共3页 Clinical Journal Of Chinese Medicine
关键词 双柏散 血循毒蛇咬伤 外敷 Shuangbai San Venomous snake bite External application
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